PD-1 INHIBITION CAN BE COMBINED WITH IL-12 IN SUBJECTS WITH RECURRENT GLIOBLASTOMA

被引:0
|
作者
Chiocca, Ennio [1 ]
Lukas, Rimas [2 ]
Rao, Ganesh [3 ]
Buck, Jill [4 ]
Demars, Nathan [4 ]
Smith, Amy [4 ]
Miao, John [4 ]
Zhou, John [4 ]
Gelb, Arnold [4 ]
Cooper, Laurence [4 ]
机构
[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Neurosurg, Boston, MA 02115 USA
[2] Northwestern Med, Chicago, IL USA
[3] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[4] Ziopharm Oncol Inc, Boston, MA USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
ATIM-25
引用
收藏
页码:6 / 7
页数:2
相关论文
共 50 条
  • [41] IL-12 ARMORED CAR T CELL THERAPY FOR HETEROGENEOUS GLIOBLASTOMA
    Shen, Steven
    Cook, Sarah
    Suryadevara, Carter
    Hotchkiss, Kelly
    Snyder, David
    Sanchez-Perez, Luis
    Sampson, John
    NEURO-ONCOLOGY, 2022, 24 : 221 - 221
  • [42] Molecular mechanisms for IL-12 deficiency in a patient with recurrent infections
    Uthaisangsook, S
    Hitchcock, R
    James-Yarish, M
    Takahashi, A
    Day, NK
    Good, RA
    Haraguchi, S
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 105 (01) : S218 - S219
  • [43] IL-12 and Type I IFN differentially program CD8 T cells for PD-1 expression levels and tumor control
    Harris, Lynn Heltemes
    Gerner, Michael
    Mescher, Matthew
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [44] IL-12 ARMORED CAR T CELL THERAPY FOR HETEROGENEOUS GLIOBLASTOMA
    Shen, Steven
    Reedy, Jessica
    Suryadevara, Carter
    Hotchkiss, Kelly
    Snyder, David
    Sanchez-Perez, Luis
    Sampson, John
    NEURO-ONCOLOGY, 2021, 23 : 167 - 167
  • [45] PD-1 immunotherapy for recurrent or metastatic HNSCC
    Ferris, Robert L.
    Licitra, Lisa
    LANCET, 2019, 394 (10212): : 1882 - 1884
  • [46] RECURRENT VASCULITIS IN TWO PATIENTS WITH IL-12/IL-23 B1 RECEPTOR DEFICIENCY
    Zinovieva, N. V.
    Konopliannikova, Y. E.
    Kovalev, G. I.
    Bustamante, J.
    Boisson-Dupuis, S.
    Casanova, J-L
    Shcherbina, A.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2012, 32 : 187 - 187
  • [47] IL-12 and IL-23 pathway inhibition in inflammatory bowel disease
    Verstockt, Bram
    Salas, Azucena
    Sands, Bruce E.
    Abraham, Clara
    Leibovitzh, Haim
    Neurath, Markus
    Vande Casteele, Niels
    NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2023, 20 (07) : 433 - 446
  • [48] Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10
    Aste-Amezaga, M
    Ma, XJ
    Sartori, A
    Trinchieri, G
    JOURNAL OF IMMUNOLOGY, 1998, 160 (12): : 5936 - 5944
  • [49] IL-12 and IL-23 pathway inhibition in inflammatory bowel disease
    Bram Verstockt
    Azucena Salas
    Bruce E. Sands
    Clara Abraham
    Haim Leibovitzh
    Markus F. Neurath
    Niels Vande Casteele
    Nature Reviews Gastroenterology & Hepatology, 2023, 20 : 433 - 446
  • [50] Selective pharmacologic inhibition of murine and human IL-12-dependent Th1 differentiation and IL-12 signaling
    Coon, ME
    Diegel, M
    Leshinsky, N
    Klaus, SJ
    JOURNAL OF IMMUNOLOGY, 1999, 163 (12): : 6567 - 6574