Highly enantioselective synthesis of a fluorescent amino acid

被引：16
|
作者：
Kele, P
Sui, GD
Huo, Q
Leblanc, RM
机构：
[1] Univ Miami, Ctr Supramol Sci, Coral Gables, FL 33124 USA
[2] Univ Miami, Dept Chem, Coral Gables, FL 33124 USA
来源：
TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 24期
关键词：
D O I：
10.1016/S0957-4166(00)00459-6
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A high enantiomeric excess (>99.5%) synthesis of L- 2-amino-3-(7-methoxy-4-coumaryl) propionic acid (L-Amp) is described. The two step synthesis route of this non-proteinogenic amino acid includes an oxazinone derivative as glycine enolate, which is alkylated with the fluorogenic group. (C) 2001 Published by Elsevier Science Ltd.
引用
收藏
页码：4959 / 4963
页数：5
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