Bugs on trial:: the case of Helicobacter pylori and autoimmunity

被引：109
作者：
Appelmelk, BJ
Faller, G
Claeys, D
Kirchner, T
Vandenbroucke-Grauls, CMJE
机构：
[1] Free Univ Amsterdam, Sch Med, Dept Med Microbiol, NL-1081 BT Amsterdam, Netherlands
[2] Univ Erlangen Nurnberg, Inst Pathol, D-91054 Erlangen, Germany
[3] CHU Vaudois, Cent Lab Clin Chem, CH-1011 Lausanne, Switzerland
来源：
IMMUNOLOGY TODAY | 1998年 / 19卷 / 07期
关键词：
D O I：
10.1016/S0167-5699(98)01281-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Helicobacter pylori infection induces autoantibodies to gastric H+K+-ATPase similar to those found in autoimmune gastritis and pernicious anaemia (AIG/PA). Here Ben Appelmelk and colleagues consider the possibility that H. pylori infection triggers an autoimmune process that leads to gastric atrophy and AIG/PA.
引用
收藏
页码：296 / 299
页数：4
相关论文
共 35 条
[1]   Reactivities of Lewis antigen monoclonal antibodies with the lipopolysaccharides of Helicobacter pylori strains isolated from patients with gastroduodenal diseases in Japan [J].
Amano, K ;
Hayashi, S ;
Kubota, T ;
Fujii, N ;
Yokota, S .
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1997, 4 (05) :540-544
[2]   Molecular mimicry between Helicobacter pylori and the host [J].
Appelmelk, BJ ;
Negrini, R ;
Moran, AP ;
Kuipers, EJ .
TRENDS IN MICROBIOLOGY, 1997, 5 (02) :70-73
[3]   Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity [J].
Appelmelk, BJ ;
SimoonsSmit, I ;
Negrini, R ;
Moran, AP ;
Aspinall, GO ;
Forte, JG ;
DeVries, T ;
Quan, H ;
Verboom, T ;
Maaskant, JJ ;
Ghiara, P ;
Kuipers, EJ ;
Bloemena, E ;
Tadema, TM ;
Townsend, RR ;
Tyagarajan, K ;
Crothers, JM ;
Monteiro, MA ;
Savio, A ;
DeGraaff, J .
INFECTION AND IMMUNITY, 1996, 64 (06) :2031-2040
[4]  
APPELMELK BJ, IN PRESS H PYLORI BA
[5]  
BOTTAZZO GF, 1983, LANCET, V2, P1115
[6]   A STUDY OF AUTOIMMUNE GASTRITIS IN THE POSTPARTUM PERIOD AND AT A 5-YEAR FOLLOW-UP [J].
BURMAN, P ;
KAMPE, O ;
KRAAZ, W ;
LOOF, L ;
SMOLKA, A ;
KARLSSON, A ;
KARLSSONPARRA, A .
GASTROENTEROLOGY, 1992, 103 (03) :934-942
[7]   Neonatal injection of native proton pump antigens induces autoimmune gastritis in mice [J].
Claeys, D ;
Saraga, E ;
Rossier, BC ;
Kraehenbuhl, JP .
GASTROENTEROLOGY, 1997, 113 (04) :1136-1145
[8]  
CLAEYS D, IN PRESS GASTROENTER
[9]  
DElios MM, 1997, J IMMUNOL, V158, P962
[10]   ASSOCIATION OF CAMPYLOBACTER-PYLORI WITH INDUCED EXPRESSION OF CLASS-II TRANSPLANTATION ANTIGENS ON GASTRIC EPITHELIAL-CELLS [J].
ENGSTRAND, L ;
SCHEYNIUS, A ;
PAHLSON, C ;
GRIMELIUS, L ;
SCHWAN, A ;
GUSTAVSSON, S .
INFECTION AND IMMUNITY, 1989, 57 (03) :827-832
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