Anti-Cancer Activity of Andrographolide: A Review

被引：3

作者：

Yerragunta, Vishwanadham ^{[1
]}

Waghray, Kavita ^{[1
]}

Shivraj ^{[2
]}

Subhashini, N. J. P. ^{[2
]}

机构：

[1] Osmania Univ, Univ Coll Technol, Dept Pharm, Hyderabad, Telangana, India

[2] Osmania Univ, Univ Coll Sci, Dept Chem, Hyderabad, Telangana, India

来源：

JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL | 2021年 / 33卷 / 43B期

关键词：

Andrographolide; Andrographis paniculata; anti-cancer activity; CELL-CYCLE ARREST; PANICULATA EXTRACT; CANCER CELLS; COMMON COLD; APOPTOSIS;

D O I：

10.9734/JPRI/2021/v33i43B32519

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Andrographolide, is a chemical compound obtained from the Andrographis paniculata (FamilyAcanthaceae), maybe a diterpene lactone ring is responsible for various biological activities like anti-inflammation, anti-microbial anti-cancer, anti-obesity, anti-diabetes, anti-oxidant immunomodulatory, antiseptic, hypolipidemic, cardioprotective, hepatoprotective, neuroprotective effects and other biological activities. In Current research activities worldwide to exhibit the beneficial role of Andrographolide are continuously enriching the therapeutic arsenal of this important Phyto molecule. For this purpose, several databases were accustomed explore for the anticancer/cytotoxic effects of the andrographolide in pre-clinical and clinical studies. During this report, an attempt has been given to spotlight the research findings, related to therapeutic potentials and up-to-date development within the pharmacological activities of andrographolide. Andrographolide is often one of the potential agents within the treatment of cancer.

引用

页码：1 / 9

页数：9

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