Palladium catalyzed addition of arylboronic acid or indole to nitriles: synthesis of aryl ketones

被引：44
|
作者：
Das, Tuluma [1 ]
Chakraborty, Amarnath [1 ]
Sarkar, Amitabha [1 ]
机构：
[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Kolkata 700032, India
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 52期
关键词：
Palladium; Pyrazolylpyridine; Addition reaction; Aryl ketone; 3-Acyl-indole; FRIEDEL-CRAFTS ACYLATION; ONE-POT SYNTHESIS; PALLADIUM(II)-CATALYZED ADDITION; CARBOXYLIC-ACIDS; IONIC LIQUIDS; C-3; ARYLATION; 3-ACYLINDOLES; ACTIVATION; PYRROLES; 3-AROYLINDOLES;
D O I：
10.1016/j.tetlet.2014.11.009
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Aryl ketones can be synthesized conveniently by a palladium catalyzed addition of arylboronic acid to nitriles in aqueous triflic acid. This catalytic system was extended to the addition of unprotected indoles to nitriles under a slightly modified condition to produce 3-acyl indoles in good yields. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7198 / 7202
页数：5
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