Utilizing Chemical Raman Enhancement: A Route for Metal Oxide Support-Based Biodetection

被引：97

作者：

Hurst, Sarah J. ^{[1
]}

Fry, H. Christopher ^{[1
]}

Gosztola, David J. ^{[1
]}

Rajh, Tijana ^{[1
]}

机构：

[1] Argonne Natl Lab, Ctr Nanoscale Mat, Argonne, IL 60439 USA

来源：

JOURNAL OF PHYSICAL CHEMISTRY C | 2011年 / 115卷 / 03期

关键词：

CHARGE-TRANSFER; TIO2; NANOPARTICLES; ELECTRON-TRANSFER; QUANTUM DOTS; SCATTERING; MOLECULES; SPECTROSCOPY; SERS; 4-MERCAPTOPYRIDINE; NANOCRYSTALS;

D O I：

10.1021/jp1096162

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Raman scattering enhancement was observed in systems where different metal oxide semiconductors (TiO2, Fe2O3, ZrO2, and CeO2) were modified with enediol ligands. The intensity of Raman scattering was dependent on laser frequency and correlated with the extinction coefficient of the CT complex of the enediol ligands and nanoparticles. The mechanism of Raman enhancement was studied by varying both the chemical composition of the enediol ligand and the chemical composition (and crystal structure) of the nanoparticles. We found that the intensity of the Raman signal depends on the number of surface binding sites, electron density of the ligands, and their dipole moment. Changes in chemical composition caused variations in the intensity, frequency, and number of Raman bands observed. We also showed that Raman scattering is observed for the bioconjugated system, where a peptide is linked to the surface of the particle through a catechol linker, and further investigated the potential for such a system in the development of Raman-based in vivo and in vitro biodetection, cell labeling and imaging, and nanotherapeutic strategies.

引用

页码：620 / 630

页数：11

共 62 条

[1] Ultrastable Iron Oxide Nanoparticle Colloidal Suspensions Using Dispersants with Catechol-Derived Anchor Groups [J].

Amstad, Esther ;

Gillich, Torben ;

Bilecka, Idalia ;

Textor, Marcus ;

Reimhult, Erik .

NANO LETTERS, 2009, 9 (12) :4042-4048

[2] The role of charge-transfer states of the metal-adsorbate complex in surface-enhanced Raman scattering [J].

Arenas, JF ;

Soto, J ;

Tocón, IL ;

Fernández, DJ ;

Otero, JC ;

Marcos, JI .

JOURNAL OF CHEMICAL PHYSICS, 2002, 116 (16) :7207-7216

[3] A SPECTROPHOTOMETRIC INVESTIGATION OF THE INTERACTION OF IODINE WITH AROMATIC HYDROCARBONS [J].

BENESI, HA ;

HILDEBRAND, JH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1949, 71 (08) :2703-2707

[4]

BRUSOV KN, 1988, KOLLOID ZH, V50, P627

[5] Fe2O3 nanoparticle structures investigated by X-ray absorption near-edge structure, surface modifications, and model calculations [J].

Chen, LX ;

Liu, T ;

Thurnauer, MC ;

Csencsits, R ;

Rajh, T .

JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (34) :8539-8546

[6] XAFS studies of surface structures of TiO2 nanoparticles and photocatalytic reduction of metal ions [J].

Chen, LX ;

Rajh, T ;

Wang, ZY ;

Thurnauer, MC .

JOURNAL OF PHYSICAL CHEMISTRY B, 1997, 101 (50) :10688-10697

[7] Determination of the degree of charge-transfer contributions to surface-enhanced Raman spectroscopy [J].

Chenal, Cat ;

Birke, Ronald L. ;

Lombardi, John R. .

CHEMPHYSCHEM, 2008, 9 (11) :1617-1623

[8] Photophysics of dopamine-modified quantumdots and effects on biological systems [J].

Clarke, SJ ;

Hollmann, CA ;

Zhang, ZJ ;

Suffern, D ;

Bradforth, SE ;

Dimitrijevic, NM ;

Minarik, WG ;

Nadeau, JL .

NATURE MATERIALS, 2006, 5 (05) :409-417

[9] Binding of catechols to mononuclear titanium(IV) and to 1-and 5-nm TiO2 nanoparticles [J].

Creutz, Carol ;

Chou, Mei H. .

INORGANIC CHEMISTRY, 2008, 47 (09) :3509-3514

[10] Selective photocatalytic decomposition of nitrobenzene using surface modified TiO2 nanoparticles [J].

Cropek, Donald ;

Kemme, Patricia A. ;

Makarova, Olga V. ;

Chen, Lin X. ;

Rajh, Tijana .

JOURNAL OF PHYSICAL CHEMISTRY C, 2008, 112 (22) :8311-8318

← 1 2 3 4 5 6 7 →