Phytochemicals for the treatment of COVID-19

被引：18
作者：
Espano, Erica [1 ]
Kim, Jiyeon [1 ]
Lee, Kiho [1 ]
Kim, Jeong-Ki [1 ]
机构：
[1] Korea Univ, Coll Pharm, Dept Pharm, Sejong 30019, South Korea
来源：
JOURNAL OF MICROBIOLOGY | 2021年 / 59卷 / 11期
关键词：
antivirals; alkaloids; coronaviruses; COVID-19; flavonoids; phytochemicals; natural products; SARS-CoV-2; SARS-COV-2; PROTEASE; INHIBIT; ANDROGRAPHOLIDE; REPLICATION; EXTRACT; TMPRSS2;
D O I：
10.1007/s12275-021-1467-z
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.
引用
收藏
页码：959 / 977
页数：19
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