Use of a modified Allium test with nanoTiO2

被引：45

作者：

Klancnik, K. ^{[1
]}

Drobne, D. ^{[1
]}

Valant, J. ^{[1
]}

Koce, J. Dolenc ^{[1
]}

机构：

[1] Univ Ljubljana, Biotech Fac, Dept Biol, SL-1000 Ljubljana, Slovenia

来源：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 2011年 / 74卷 / 01期

关键词：

Album test; Mitotic index; Nanoparticles; UV; TiO2; Toxicity; TITANIUM-DIOXIDE NANOPARTICLES; DNA-DAMAGE; COLLOIDAL SUSPENSIONS; SILVER NANOPARTICLES; TOXICITY; TIO2; GROWTH; CYTOTOXICITY; NANO-TIO2; PARTICLES;

D O I：

10.1016/j.ecoenv.2010.09.001

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Extensive production and wide application of TiO2 nanoparticles has stimulated research on its potential biological effects on different groups of organisms but the interaction of TiO2 nanoparticles with higher plants remains poorly understood. We have studied the effect of TiO2 nanoparticles on Album cepa using a modification of the conventional Album test with nanoparticles suspended in distilled water as opposed to growth medium. Nanoparticulate TiO2 was found to have low toxic potential and the mitotic index was among the most sensitive measures of the effect of nano-TiO2. We conclude that modified Allium test is suitable to provide comparative data on the biological potential of a variety of nanoparticles and could be used in a tiered approach to nanotoxicity testing. (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：85 / 92

页数：8

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