Electrospinning Nanofibers Gelatin scaffolds: Nanoanalysis of properties and optimizing the process for tissue engineering functional

被引:6
作者
Jalili, Mohammad [1 ]
Mozaffari, Abolfazl [1 ]
Gashti, Mazeyar [2 ]
Parsania, Masoud [3 ]
机构
[1] Islamic Azad Univ, Dept Text Engn, Yazd Branch, Yazd, Iran
[2] PRE Labs Inc, Res & Dev Lab, 3302 Appaloosa Rd,Unit 3, Kelowna, BC, Canada
[3] Islamic Azad Univ, Dept Microbiol, Fac Med, Tehran Med Sci, Tehran, Iran
来源
JOURNAL OF NANOANALYSIS | 2019年 / 6卷 / 04期
关键词
Electrospinning; Gelatin; Morphology; Nanofibers; Tissue Engineering;
D O I
10.22034/JNA.2019.669860
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Electrospinning has been recognized as an efficient technique for the fabrication of polymer nanofibers. Recently, various polymers have successfully been electrospun into ultrafine fibers. Electrospinning is an extremely promising method for the preparation of tissue engineering scaffolds. In this study, nanofibers gelatin was electrospun at 20% v/v optimized content. To produce gelatin nanofibers optimally, production parameters need to be investigated. In the electrospinning, device (voltage and distance) parameters were determined to be effective; as a result, these parameters were researched and the influences of electrospinning device parameters (voltage & distance) on properties of gelatin nanofibers were evaluated. These parameters affected the diameter size, uniformity, hydrophilicity and thermal degradation of electrospun gelatin nanofibers. All of these properties were examined by SEM, FTIR, CA, BET, XRAY and TGA tests and finally optimum gelatin nanofibers can be used in many applications including cell culture, drug delivery and tissue engineering.
引用
收藏
页码:289 / 298
页数:10
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