A novel ferrocenyl diselenide for the catalytic asymmetric aryl transfer to aldehydes

被引：57

作者：

Bolm, C ^{[1
]}

Kesselgruber, M ^{[1
]}

Grenz, A ^{[1
]}

Hermanns, N ^{[1
]}

Hildebrand, JP ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

NEW JOURNAL OF CHEMISTRY | 2001年 / 25卷 / 01期

关键词：

D O I：

10.1039/b003237i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An oxazolinyl ferrocenyl diselenide was synthesised by directed ortho-metalation and used as catalyst precursor in the asymmetric addition of diethyl- and diphenylzinc to various aldehydes, yielding synthetically useful secondary alcohols, of which some are difficult to access using other catalytic methodologies. Enantioselectivities of up to 44% for the former and up to 85% for the latter transformations were obtained.

引用

页码：13 / 15

页数：3

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