Imaging of peroxynitrite in drug-induced acute kidney injury with a near-infrared fluorescence and photoacoustic dual-modal molecular probe

被引：53

作者：

Liu, Hong-Wen ^{[1
]}

Zhang, Haiyang ^{[1
]}

Lou, Xiaofeng ^{[1
]}

Teng, Lili ^{[1
]}

Yuan, Jie ^{[1
]}

Yuan, Lin ^{[1
]}

Zhang, Xiao-Bing ^{[1
]}

Tan, Weihong ^{[1
]}

机构：

[1] Hunan Univ, Mol Sci & Biomed Lab MBL, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 58期

基金：

中国国家自然科学基金; 国家重点研发计划; 中国博士后科学基金;

关键词：

ENDOGENOUS PEROXYNITRITE; MITOCHONDRIA; VISUALIZATION; CELLS;

D O I：

10.1039/d0cc01621g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A FRET-based probe for mapping the fluctuation of ONOO(-)in cisplatin-induced acute kidney injury was constructed. It exhibits ratiometric near infrared fluorescence and a dramatic decrease of its peak absorbance at 719 nm upon addition of ONOO(-)that is converted into remarkable signal changes in fluorescence and photoacoustic images respectively.

引用

页码：8103 / 8106

页数：4

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