Human Epidermal Growth Factor Receptor 2 as a Molecular Biomarker for Metastatic Colorectal Cancer

被引:16
作者
Sartore-Bianchi, Andrea [1 ]
Marsoni, Silvia [1 ,2 ]
Siena, Salvatore [1 ,3 ]
机构
[1] Grande Osped Metropolitano Niguarda, Niguarda Canc Ctr, Milan, Italy
[2] IRCCS, Candiolo Canc Inst FPO, SP 142 Km 3-95, I-10060 Candiolo, TO, Italy
[3] Univ Milan, Dipartimento Oncol & Ematooncol, Milan, Italy
关键词
D O I
10.1001/jamaoncol.2017.3323
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:19 / 20
页数:2
相关论文
共 8 条
[1]   A Molecularly Annotated Platform of Patient-Derived Xenografts ("Xenopatients") Identifies HER2 as an Effective Therapeutic Target in Cetuximab-Resistant Colorectal Cancer [J].
Bertotti, Andrea ;
Migliardi, Giorgia ;
Galimi, Francesco ;
Sassi, Francesco ;
Torti, Davide ;
Isella, Claudio ;
Cora, Davide ;
Di Nicolantonio, Federica ;
Buscarino, Michela ;
Petti, Consalvo ;
Ribero, Dario ;
Russolillo, Nadia ;
Muratore, Andrea ;
Massucco, Paolo ;
Pisacane, Alberto ;
Molinaro, Luca ;
Valtorta, Emanuele ;
Sartore-Bianchi, Andrea ;
Risio, Mauro ;
Capussotti, Lorenzo ;
Gambacorta, Marcello ;
Siena, Salvatore ;
Medico, Enzo ;
Sapino, Anna ;
Marsoni, Silvia ;
Comoglio, Paolo M. ;
Bardelli, Alberto ;
Trusolino, Livio .
CANCER DISCOVERY, 2011, 1 (06) :508-523
[2]   Pertuzumab plus trastuzumab for HER2-amplified/overexpressed metastatic colorectal cancer (mCRC): Interim data from MyPathway [J].
Hurwitz, Herbert ;
Raghav, Kanwal Pratap Singh ;
Burris, Howard A. ;
Kurzrock, Razelle ;
Sweeney, Christopher ;
Meric-Bernstam, Funda ;
Vanderwalde, Ari M. ;
Spigel, David R. ;
Bose, Ron ;
Fakih, Marwan ;
Swanton, Charles ;
Guo, Shuangli ;
Bernaards, Coen ;
Beattie, Mary Stanley ;
Sommer, Nicolas ;
Hainsworth, John D. .
JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
[3]   Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade [J].
Le, Dung T. ;
Durham, Jennifer N. ;
Smith, Kellie N. ;
Wang, Hao ;
Bartlett, Bjarne R. ;
Aulakh, Laveet K. ;
Lu, Steve ;
Kemberling, Holly ;
Wilt, Cara ;
Luber, Brandon S. ;
Wong, Fay ;
Azad, Nilofer S. ;
Rucki, Agnieszka A. ;
Laheru, Dan ;
Donehower, Ross ;
Zaheer, Atif ;
Fisher, George A. ;
Crocenzi, Todd S. ;
Lee, James J. ;
Greten, Tim F. ;
Duffy, Austin G. ;
Ciombor, Kristen K. ;
Eyring, Aleksandra D. ;
Lam, Bao H. ;
Joe, Andrew ;
Kang, S. Peter ;
Holdhoff, Matthias ;
Danilova, Ludmila ;
Cope, Leslie ;
Meyer, Christian ;
Zhou, Shibin ;
Goldberg, Richard M. ;
Armstrong, Deborah K. ;
Bever, Katherine M. ;
Fader, Amanda N. ;
Taube, Janis ;
Housseau, Franck ;
Spetzler, David ;
Xiao, Nianqing ;
Pardoll, Drew M. ;
Papadopoulos, Nickolas ;
Kinzler, Kenneth W. ;
Eshleman, James R. ;
Vogelstein, Bert ;
Anders, Robert A. ;
Diaz, Luis A., Jr. .
SCIENCE, 2017, 357 (6349) :409-413
[4]   HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials [J].
Richman, Susan D. ;
Southward, Katie ;
Chambers, Philip ;
Cross, Debra ;
Barrett, Jennifer ;
Hemmings, Gemma ;
Taylor, Morag ;
Wood, Henry ;
Hutchins, Gordon ;
Foster, Joseph M. ;
Oumie, Assa ;
Spink, Karen G. ;
Brown, Sarah R. ;
Jones, Marc ;
Kerr, David ;
Handley, Kelly ;
Gray, Richard ;
Seymour, Matthew ;
Quirke, Philip .
JOURNAL OF PATHOLOGY, 2016, 238 (04) :562-570
[5]   Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial [J].
Sartore-Bianchi, Andrea ;
Trusolino, Livio ;
Martino, Cosimo ;
Bencardino, Katia ;
Lonardi, Sara ;
Bergamo, Francesca ;
Zagonel, Vittorina ;
Leone, Francesco ;
Depetris, Ilaria ;
Martinelli, Erika ;
Troiani, Teresa ;
Ciardiello, Fortunato ;
Racca, Patrizia ;
Bertotti, Andrea ;
Siravegna, Giulia ;
Torri, Valter ;
Amatu, Alessio ;
Ghezzi, Silvia ;
Marrapese, Giovanna ;
Palmeri, Laura ;
Valtorta, Emanuele ;
Cassingena, Andrea ;
Lauricella, Calogero ;
Vanzulli, Angelo ;
Regge, Daniele ;
Veronese, Silvio ;
Comoglio, Paolo M. ;
Bardelli, Alberto ;
Marsoni, Silvia ;
Siena, Salvatore .
LANCET ONCOLOGY, 2016, 17 (06) :738-746
[6]   Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology [J].
Sepulveda, Antonia R. ;
Hamilton, Stanley R. ;
Allegra, Carmen J. ;
Grody, Wayne ;
Cushman-Vokoun, Allison M. ;
Funkhouser, William K. ;
Kopetz, Scott E. ;
Lieu, Christopher ;
Lindor, Noralane M. ;
Minsky, Bruce D. ;
Monzon, Federico A. ;
Sargent, Daniel J. ;
Singh, Veena M. ;
Willis, Joseph ;
Clark, Jennifer ;
Colasacco, Carol ;
Rumble, R. Bryan ;
Temple-Smolkin, Robyn ;
Ventura, Christina B. ;
Nowak, Jan A. .
JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (13) :1453-+
[7]  
Siena S, AACR ANN M 2017 WASH
[8]   Assessment of a HER2 scoring system for colorectal cancer: results from a validation study [J].
Valtorta, Emanuele ;
Martino, Cosimo ;
Sartore-Bianchi, Andrea ;
Penaullt-Llorca, Frederique ;
Viale, Giuseppe ;
Risio, Mauro ;
Rugge, Massimo ;
Grigioni, Walter ;
Bencardino, Katia ;
Lonardi, Sara ;
Zagonel, Vittorina ;
Leone, Francesco ;
Noe, Johannes ;
Ciardiello, Fortunato ;
Pinto, Carmine ;
Labianca, Roberto ;
Mosconi, Stefania ;
Graiff, Claudio ;
Aprile, Giuseppe ;
Frau, Barbara ;
Garufi, Carlo ;
Loupakis, Fotios ;
Racca, Patrizia ;
Tonini, Giuseppe ;
Lauricella, Calogero ;
Veronese, Silvio ;
Truini, Mauro ;
Siena, Salvatore ;
Marsoni, Silvia ;
Gambacorta, Marcello .
MODERN PATHOLOGY, 2015, 28 (11) :1481-1491