AN INTEGRATED DEVICE FOR MONITORING SINGLE CELL METABOLISM

被引：0

作者：

Yu, Bocheng ^{[1
]}

Wu, Yuting ^{[1
]}

Yu, Peng ^{[2
]}

Huang, Dong ^{[1
]}

Li, Zhihong ^{[1
]}

机构：

[1] Peking Univ, Inst Micro Nano Elect, Natl Key Lab Nano Micro Fabricat Technol, Beijing 100871, Peoples R China

[2] Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China

来源：

2019 20TH INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS & EUROSENSORS XXXIII (TRANSDUCERS & EUROSENSORS XXXIII) | 2019年

关键词：

Oxygen consumption rate measurement; Single cell; Electrochemical sensors; Microelectrodes; MICROELECTRODE ARRAY; OXYGEN;

D O I：

10.1109/transducers.2019.8808597

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper presents a single cell oxygen consumption rate monitoring device based on the electrochemical microelectrode, which features simple cell capture structure, high spatial resolution and multichannel real-time sensing. The device is fabricated with planar microfabrication techniques, therefore having the advantages of low-cost and mass production. An oxygen permeable membrane has been applied to the electrodes to enhance the sensitivity. A model based data processing method is proposed. The single cell metabolism has been monitored with drug tests.

引用

页码：744 / 747

页数：4

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