Prospective multi-center study of an automatic online seizure detection system for epilepsy monitoring units

被引：72

作者：

Fuerbass, F. ^{[1
]}

Ossenblok, P. ^{[3
]}

Hartmann, M. ^{[1
]}

Perko, H. ^{[1
]}

Skupch, A. M. ^{[1
]}

Lindinger, G. ^{[4
]}

Elezi, L. ^{[2
]}

Pataraia, E. ^{[4
]}

Colon, A. J. ^{[5
]}

Baumgartner, C. ^{[2
]}

Kluge, T. ^{[1
]}

机构：

[1] AIT Austrian Inst Technol GmbH, Dept Safety & Secur, Vienna, Austria

[2] Gen Hosp Hietzing, Neurol Ctr Rosenhuegel, Dept Neurol 2, Vienna, Austria

[3] Heeze & Maastricht UMC, Acad Ctr Epileptol, Clin Phys, Heeze, Netherlands

[4] Med Univ Vienna, Dept Clin Neurol, Vienna, Austria

[5] Heeze & Maastricht UMC, Acad Ctr Epileptol, Dept Clin Neurophysiol, NL-5590 AB Heeze, Netherlands

来源：

CLINICAL NEUROPHYSIOLOGY | 2015年 / 126卷 / 06期

关键词：

Epileptic seizure detection; Automatic; Online; Parameter free; Alarm device; Prospective multi-center study; SAFETY OUTCOMES; SCALP EEG; RECOGNITION;

D O I：

10.1016/j.clinph.2014.09.023

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: A method for automatic detection of epileptic seizures in long-term scalp-EEG recordings called EpiScan will be presented. EpiScan is used as alarm device to notify medical staff of epilepsy monitoring units (EMUs) in case of a seizure. Methods: A prospective multi-center study was performed in three EMUs including 205 patients. A comparison between EpiScan and the Persyst seizure detector on the prospective data will be presented. In addition, the detection results of EpiScan on retrospective EEG data of 310 patients and the public available CHB-MIT dataset will be shown. Results: A detection sensitivity of 81% was reached for unequivocal electrographic seizures with false alarm rate of only 7 per day. No statistical significant differences in the detection sensitivities could be found between the centers. The comparison to the Persyst seizure detector showed a lower false alarm rate of EpiScan but the difference was not of statistical significance. Conclusions: The automatic seizure detection method EpiScan showed high sensitivity and low false alarm rate in a prospective multi-center study on a large number of patients. Significance: The application as seizure alarm device in EMUs becomes feasible and will raise the efficiency of video-EEG monitoring and the safety levels of patients. (C) 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

引用

页码：1124 / 1131

页数：8

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