RAPID CHARACTERIZATION OF PEPTIDE SECONDARY STRUCTURE BY FT-IR SPECTROSCOPY

被引:1
作者
Adochitei, Adriana [1 ]
Drochioiu, Gabi [1 ]
机构
[1] Alexandru Ioan Cuza Univ, Fac Chem, Dept Chem, Iasi 700506, Romania
关键词
FT-IR; protein structure; peptide conformation; CD spectroscopy; IDENTIFICATION; BINDING; SPECTRA; WATER;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Use of peptides and proteins in many different applications requires a more detailed structural characterization of these in different environments. Information on structural properties of peptides and proteins in various solvents are also given by Fourier transform infrared (FT-IR) spectroscopy. Here, we investigate the amide I, II, and Ill bands of peptides using both FT-IR spectra and their second derivatives. This paper reveals a large body of information obtained by FT-IR technique that can be used to understand the structure and stability of some peptides and proteins in different environments. Circular dichroism (CD) spectroscopy support data obtained within FT-IR experiments.
引用
收藏
页码:783 / 791
页数:9
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