Primary Leiomyosarcoma of the Prostate With Lung Metastasis: Report of a Case Diagnosed by Fine-Needle Aspiration Cytology

Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. Herein, we present a patient with primary leiomyosarcoma of the prostate with lung metastasis diagnosed primarily on fine-needle aspiration cytology. Characteristic cytological features such as small fascicles of spindle cells with blunt-ended nuclei, positivity for desmin and smooth muscle actin along with the radiological features are helpful in the correct diagnosis. Diagn. Cytopathol. 2011; 39: 700-702. (C) 2010 Wiley-Liss, Inc.