Iodine(III)-mediated intramolecular sulfeno- and selenofunctionalization of β,γ-unsaturated tosyl hydrazones and oximes

被引：62

作者：

Yu, Jing-Miao ^{[1
]}

Cai, Chun ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Chem Engn Coll, 200 Xiao Ling Wei St, Nanjing, Jiangsu, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2018年 / 16卷 / 03期

关键词：

COPPER-CATALYZED SYNTHESIS; UNACTIVATED ALKENES; SUBSTITUTED ISOXAZOLINES; CASCADE SYNTHESIS; IODINE; PYRAZOLINES; TETRAHYDROPYRIDAZINES; AMINOFLUORINATION; DIHYDROPYRAZOLES; SULFENYLATION;

D O I：

10.1039/c7ob02892j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A cascade radical cyclization/sulfenylation or selenylation of beta,gamma-unsaturated hydrazones and oximes was realized under mild conditions with phenyliodine(III) diacetate (PIDA) as the sole oxidant, leading to the construction of diversely functionalized heteroatom-containing pyrazoline and isoxazoline derivatives. This metal-free radical process is suggested to encompass a sequential C-N/O and C-S/Se bond fomation.

引用

收藏

页码：490 / 498

页数：9

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