Cross-Coupling of Aryl/Alkenyl Ethers with Aryl Grignard Reagents through Nickel-Catalyzed C-O Activation

被引：92

作者：

Xie, Lan-Gui ^{[1
,2
]}

Wang, Zhong-Xia ^{[1
,2
]}

机构：

[1] Univ Sci & Technol China, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 18期

基金：

中国国家自然科学基金;

关键词：

C-O activation; cross-coupling; Grignard reagents; homogeneous catalysis; nickel; CARBON-CARBON BONDS; UNSYMMETRICAL BIARYLS; ORGANOBORON COMPOUNDS; EFFICIENT SYNTHESIS; OXYGEN; CONSTRUCTION; ALKENYL; HALIDES; OLEFINS; ARENES;

D O I：

10.1002/chem.201003731

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The formation of a C-C bond has been achieved through the cleavage of the sp2 C-O bond of aryl/alkenyl ethers catalyzed by a nickel complex, and by using Grignard reagents as nucleophiles (see scheme). This method displays a broad substrate scope and leads to good to excellent yields of the aryl-aryl or alkenyl-aryl cross-coupling products. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4972 / 4975

页数：4

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