Oral yeast colonization in peritoneal dialysis and hemodialysis patients and renal transplant recipients

被引:9
作者
Gulcan, Aynur [1 ]
Gulcan, Erim [2 ]
Keles, Mustafa [3 ]
Aktas, Esin [4 ]
机构
[1] Dumlupinar Univ Med Fac, Microbiol & Clin Microbiol, Kutahya, Turkey
[2] Dumlupinar Univ Med Fac, Dept Nephrol, Kutahya, Turkey
[3] Mevlana Univ Med Fac, Dept Nephrol, Konya, Turkey
[4] Yildirim Beyazit Univ Med Fac, Microbiol & Clin Microbiol, Ankara, Turkey
关键词
Oral yeast colonization; Renal transplantation; Hemodialysis; Peritoneal dialysis; Risk factors; QUALITY-OF-LIFE; CANDIDA; INFECTION;
D O I
10.1016/j.cimid.2016.04.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Objective: We aimed to investigate the frequency of oral yeast colonization (OYC) and the risk factors for patients who received continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis (HD) or were renal transplant recipients (RTRs). The patients admitted to the Nephrology Clinic at Ataturk University Medical School from January through April 2013 were included in the study. A questionnaire about risk factors was filled out, and swab cultures were taken from the tongue surface of each participant. OYC was detected in 32.1% of the RTRs, 40% of the HD patients, 20.9% of the CAPD patients, and 18% of the healthy control (HC) group. Of the 42 yeast strains isolated from the renal replacement therapy groups, 26 strains (61.9%) were Candida albicans, nine (21.4%) were Candida glabrata, two (4.7%) were Candida krusei, two (4.7%) were Candida kefyr, one (2.38%) was Candida parapsilosis, and two (4.7%) were Geotrichum candidum. Risk factors for OYC in the RTRs group included antibiotic use and the presence of dental prostheses; however, in patients with chronic renal failure undergoing CAPD, only the presence of dental prostheses was found to be a statistically significant risk factor. Although OYC was mostly detected in patients with chronic kidney disease (undergoing HD, a variety of isolated yeast strains in the RTRs was noted. The rates of OYC and isolated Candida species in CAPD were similar to those of the HC group. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:47 / 52
页数:6
相关论文
共 36 条
[1]   Hospitalizations for fungal infections after initiation of chronic dialysis in the United States [J].
Abbott, KC ;
Hypolite, I ;
Tveit, DP ;
Hshieh, P ;
Cruess, D ;
Agodoa, LY .
NEPHRON, 2001, 89 (04) :426-432
[2]   Quality of life in hemodialysis and peritoneal dialysis patients in Saudi Arabia [J].
Al Wakeel, Jamal ;
Al Harbi, Ali ;
Bayoumi, Magda ;
Al-Suwaida, Karaem ;
Al Ghonaim, Mohammed ;
Mishkirye, Adel .
ANNALS OF SAUDI MEDICINE, 2012, 32 (06) :570-574
[3]   Oral fungal colonization and oral candidiasis in renal transplant patients:: The relationship to Miswak use [J].
Al-Mohaya, MA ;
Darwazeh, A ;
Al-Khudair, W .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 2002, 93 (04) :455-460
[4]  
Badiee Parisa, 2005, Exp Clin Transplant, V3, P385
[5]   High prevalence of non-albicans yeasts and detection of anti-fungal resistance in the oral flora of patients with advanced cancer [J].
Bagg, J ;
Sweeney, MP ;
Lewis, MAO ;
Coleman, D ;
Al Mosaid, A ;
Baxter, W ;
McEndrick, S ;
McHugh, S .
PALLIATIVE MEDICINE, 2003, 17 (06) :477-481
[6]  
Bonifaz Alexandro, 2010, J Oral Sci, V52, P477
[7]   HISTOPATHOLOGY, IMMUNOLOGY, AND SEROLOGY OF ORAL YEAST INFECTIONS - DIAGNOSIS OF ORAL CANDIDOSIS [J].
BUDTZJORGENSEN, E .
ACTA ODONTOLOGICA SCANDINAVICA, 1990, 48 (01) :37-43
[8]   ORAL CANDIDA - CLEARANCE, COLONIZATION, OR CANDIDIASIS [J].
CANNON, RD ;
HOLMES, AR ;
MASON, AB ;
MONK, BC .
JOURNAL OF DENTAL RESEARCH, 1995, 74 (05) :1152-1161
[9]   Oral colonization by Candida albicans [J].
Cannon, RD ;
Chaffin, WL .
CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE, 1999, 10 (03) :359-383
[10]   The role of the gastrointestinal tract in hematogenous candidiasis: From the laboratory to the bedside [J].
Cole, GT ;
Halawa, AA ;
Anaissie, EJ .
CLINICAL INFECTIOUS DISEASES, 1996, 22 :S73-S88