Value of molecular markers in the initial phase of oral anticoagulation therapy after heart valve replacement with mechanical prostheses

被引：0

作者：

Dahm, M ^{[1
]}

Lotz, J ^{[1
]}

Hafner, G ^{[1
]}

Oelert, H ^{[1
]}

Prellwitz, W ^{[1
]}

机构：

[1] Univ Mainz, Klin Herzchirurg, D-55131 Mainz, Germany

来源：

ZEITSCHRIFT FUR KARDIOLOGIE | 1998年 / 87卷

关键词：

molecular markers; anticoagulation therapy; mechanical heart valves;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In a prospective study, 39 patients following aortic or mitral valve replacement underwent investigation of molecular markers (prothrombin fragment F1+2, Factor II) in the initial phase of oral anticoagulation therapy (OAT). The results demonstrate that, despite INR being in the depicted range, the levels of the molecular markers remained high, indicating an increased risk of thromboembolic events. This leads to the conclusion that molecular markers are superior to INR in the monitoring of the early phase of OAT.

引用

页码：42 / 45

页数：4