Phenotypic heterogeneity of microbial populations under nutrient limitation

被引：20
作者：
Gasperotti, Ana [1 ]
Brameyer, Sophie [1 ]
Fabiani, Florian [1 ]
Jung, Kirsten [1 ]
机构：
[1] Ludwig Maximilians Univ Munchen, Dept Microbiol, D-82152 Martinsried, Germany
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2020年 / 62卷 / 62期
关键词：
GENE-EXPRESSION; NETWORK; SYSTEM; TIME;
D O I：
10.1016/j.copbio.2019.09.016
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Phenotypic heterogeneity is a phenomenon in which genetically identical individuals have different characteristics. This behavior can also be found in bacteria, even if they grow as monospecies in well-mixed environments such as bioreactors. Here it is discussed how phenotypic heterogeneity is generated by internal factors and how it is promoted under nutrient-limited growth conditions. A better understanding of the molecular levels that control phenotypic heterogeneity could improve biotechnological production processes.
引用
收藏
页码：160 / 167
页数：8
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