Graphite Oxide as an Auto-Tandem Oxidation-Hydration-Aldol Coupling Catalyst

被引：171

作者：

Jia, Hong-Peng ^{[1
]}

Dreyer, Daniel R. ^{[1
]}

Bielawski, Christopher W. ^{[1
]}

机构：

[1] Univ Texas Austin, Dept Chem & Biochem, Austin, TX 78712 USA

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2011年 / 353卷 / 04期

基金：

美国国家科学基金会;

关键词：

chalcones; Claisen-Schmidt condensation; graphite oxide; heterogeneous catalysis; hydration; oxidation; GRAPHENE-OXIDE; CHALCONES; NANOPARTICLES; ALCOHOLS; KETONES;

D O I：

10.1002/adsc.201000748

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Graphite oxide (GO) was found to function as an auto-tandem oxidation-hydration-aldol coupling catalyst for the formation of chalcones in a single reaction vessel. Various alkynes or alcohols were hydrated or oxidized in situ to their corresponding methyl ketones or aldehydes, respectively, which underwent a subsequent Claisen-Schmidt condensation. Each of the aforementioned reactions proceeded in the absence of metals (confirmed by inductively coupled plasma mass spectrometry, ICP-MS) and afforded a range of chalcone products in good to excellent yields from commercially available starting materials.

引用

页码：528 / 532

页数：5

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