The role of MSP I CYP1A1 gene polymorphism in the development of uterine fibroids

被引：9

作者：

Barao, Marco Antonio ^{[1
]}

Oliveira, Emerson ^{[1
]}

Vieira Gomes, Mariano Tamura ^{[1
]}

Cotrim Guerreiro da Silva, Ismael Dale ^{[1
]}

Ferreira Sartori, Marair Gracio ^{[1
]}

Batista Castello Girao, Manoel Joao ^{[1
]}

Castro, Rodrigo de Aquino ^{[1
]}

机构：

[1] Univ Fed Sao Paulo, Dept Gynecol, Sao Paulo, Brazil

来源：

FERTILITY AND STERILITY | 2010年 / 94卷 / 07期

基金：

巴西圣保罗研究基金会;

关键词：

Leiomyoma; polymorphism; CYP1A1; LEIOMYOMA; METABOLISM; GROWTH; CANCER;

D O I：

10.1016/j.fertnstert.2010.05.034

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The cytochrome P-450 1A1 (CYPA1A) gene plays an important role in the metabolization of estrogen and is therefore a candidate marker for fibroids. In a case-control study, we were unable to demonstrate any association between MSP I CYP1A1 polymorphism and the risk of leiomyoma in Brazilian women. (Fertil Steril (R) 2010;94:2783-5. (C) 2010 by American Society for Reproductive Medicine.)

引用

页码：2783 / 2785

页数：3

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