Electrocardiographic abnormalities and home blood pressure in treated elderly hypertensive patients: Japan home versus office blood pressure measurement evaluation in the elderly (J-HOME-Elderly) study

被引：8

作者：

Shibamiya, Taku ^{[2
]}

Obara, Taku ^{[2
,3
]}

Ohkubo, Takayoshi ^{[1
,2
]}

Shinki, Takahiro ^{[2
]}

Ishikura, Kazuki ^{[1
]}

Yoshida, Makoto ^{[2
]}

Satoh, Michihiro ^{[2
]}

Hashimoto, Takanao ^{[2
]}

Hara, Azusa ^{[2
]}

Metoki, Hirohito ^{[2
,4
]}

Inoue, Ryusuke ^{[5
]}

Asayama, Kei ^{[1
]}

Kikuya, Masahiro ^{[2
]}

Imai, Yutaka ^{[2
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Planning Drug Dev & Clin Evaluat, Aoba Ku, Sendai, Miyagi 9808578, Japan

[2] Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Dept Clin Pharmacol & Therapeut, Sendai, Miyagi 9808578, Japan

[3] Tohoku Univ Hosp, Dept Pharm, Sendai, Miyagi, Japan

[4] Tohoku Univ, Grad Sch Med, Dept Med Genet, Sendai, Miyagi 9808578, Japan

[5] Tohoku Univ, Grad Sch Med, Dept Med Informat, Sendai, Miyagi 9808578, Japan

来源：

HYPERTENSION RESEARCH | 2010年 / 33卷 / 07期

关键词：

LEFT-VENTRICULAR HYPERTROPHY; WHITE-COAT HYPERTENSION; TARGET-ORGAN DAMAGE; END-POINT REDUCTION; PROGNOSTIC VALUE; FOLLOW-UP; LOSARTAN INTERVENTION; MASKED HYPERTENSION; ALCOHOL INTAKE; RISK;

D O I：

10.1038/hr.2010.55

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

This study compares relationships between each of morning home blood pressure ( BP), evening home BP and office BP with electrocardiographic (ECG) abnormalities among treated hypertensive Japanese patients. We defined ECG left ventricular hypertrophy (LVH) as Sokolow-Lyon voltage and/or Cornell voltage duration product. Abnormal T waves and ST segment depression were categorized based on the Minnesota code. Office BP was calculated as the mean of four readings taken during two visits. Morning and evening home BP were calculated as the mean of five readings measured once each morning and evening for 5 days, respectively. Multivariate analysis showed that ECG-LVH in 747 hypertensives (mean age: 72 years; women: 63%) was more closely associated with morning home BP than with either office or evening home BP. Even the first reading of morning home BP on day 1 was significantly associated with ECG-LVH independently of office BP. The association between home BP and ECG-LVH increased with the cumulative number of home BP measurements. The results for abnormal T waves were similar. Home and office BP did not significantly differ between patients with and without ST segment depression. Morning home BP was more closely associated with ECG-LVH and abnormal T waves than either office or evening home BP among treated hypertensive Japanese patients. Hypertension Research (2010) 33, 670-677; doi: 10.1038/hr.2010.55; published online 30 April 2010

引用

页码：670 / 677

页数：8

共 32 条

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