Asymmetric allylation. An effective strategy for the convergent synthesis of highly functionalized homoallylic alcohols

被引：35
|
作者：
Williams, DR [1 ]
Brooks, DA [1 ]
Meyer, KG [1 ]
Clark, MP [1 ]
机构：
[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 40期
基金：
日本学术振兴会;
关键词：
D O I：
10.1016/S0040-4039(98)01557-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A survey of stereoselective syntheses of highly-functionalized homoallylic alcohols is described via asymmetric allylation. initial transmetalation from an allylic stannane to a C-2 symmetric chiral borane controller is followed by low temperature addition to aldehydes efficiently effecting convergent strategies to complex targets. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：7251 / 7254
页数：4
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