A glassy carbon electrode with electrodeposited silver nanoparticles for aptamer based voltammetric determination of trinitrotoluene using riboflavin as a redox probe

被引：28

作者：

Roushani, Mahmoud ^{[1
]}

Shahdost-fard, Faezeh ^{[1
]}

机构：

[1] Ilam Univ, Dept Chem, POB 69315-516, Ilam, Iran

来源：

MICROCHIMICA ACTA | 2018年 / 185卷 / 12期

关键词：

TNT; Aptasensor; AgNPs; Electrodeposition; Aptasensig assay; ELECTROCHEMICAL REDUCTION; GOLD-NANOPARTICLES; GRAPHENE OXIDE; TNT DETECTION; APTASENSOR; OXIDATION; LABEL; ELECTROCHEMILUMINESCENCE; 2,4,6-TRINITROTOLUENE; NANOCOMPOSITES;

D O I：

10.1007/s00604-018-3098-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An electrochemical nanoaptasensor is described that is based on the use of a glassy carbon electrode (GCE) modified with electrodeposited silver nanoparticles (AgNPs). An aptamer (Apt) against trinitrotoluene (TNT) was then immobilized on the AgNPs. The addition of TNT to the modified GCE leads to decrease in peak current (typically measured at a potential of -0.45V vs. Ag/AgCl) of riboflavin which acts as an electrochemical probe. Even small changes in the surface (as induced by binding of Apt to TNT) alter the interfacial properties. As a result, the LOD is lowered to 33 aM, and the dynamic range extends from 0.1 fM to 10M without sacrificing specificity.

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页数：8

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共 33 条

[21] Hybrid Aptanner-Antibody Linked Fluorescence Resonance Energy Transfer Based Detection of Trinitrotoluene [J].

Sabherwal, Priyanka ;

Shorie, Munish ;

Pathania, Preeti ;

Chaudhary, Shilpa ;

Bhasin, K. K. ;

Bhalla, Vijayender ;

Suri, C. Raman .

ANALYTICAL CHEMISTRY, 2014, 86 (15) :7200-7204

[22] The use of a signal amplification strategy for the fabrication of a TNT impedimetric nanoaptasensor based on electrodeposited NiONPs immobilized onto a GCE surface [J].

Shandost-fard, Faezeh ;

Roushani, Mahmoud .

SENSORS AND ACTUATORS B-CHEMICAL, 2017, 246 :848-853

[23] Designing an ultra-sensitive aptasensor based on an AgNPs/thiol-GQD nanocomposite for TNT detection at femtomolar levels using the electrochemical oxidation of Rutin as a redox probe [J].

Shandost-fard, Faezeh ;

Roushani, Mahmoud .

BIOSENSORS & BIOELECTRONICS, 2017, 87 :724-731

[24] Highly selective and sensitive adenosine aptasensor based on platinum nanoparticles as catalytical label for amplified detection of biorecognition events through H2O2 reduction [J].

Shandost-fard, Faezeh ;

Salimi, Abdollah ;

Khezrian, Somayeh .

BIOSENSORS & BIOELECTRONICS, 2014, 53 :355-362

[25] Ultrasensitive determination of 2,4,6-trinitrotoluene by exploiting the strongly enhanced electrochemiluminescence of an assembly between CdSe and graphene quantum dots and its quenching by TNT [J].

Shi, Jian-Jun ;

Meng, Lei-Xia ;

Yang, Ping .

MICROCHIMICA ACTA, 2017, 184 (01) :73-80

[26] Highly Selective Rational Design of Peptide-Based Surface Plasmon Resonance Sensor for Direct Determination of 2,4,6-trinitrotoluene (TNT) Explosive [J].

Wang, Jin ;

Muto, Masaki ;

Yatabe, Rui ;

Tahara, Yusuke ;

Onodera, Takeshi ;

Tanaka, Masayoshi ;

Okochi, Mina ;

Toko, Kiyoshi .

SENSORS AND ACTUATORS B-CHEMICAL, 2018, 264 :279-284

[27] Turn-On and Near-Infrared Fluorescent Sensing for 2,4,6-Trinitrotoluene Based on Hybrid (Gold Nanorod)-(Quantum Dots) Assembly [J].

Xia, Yunsheng ;

Song, Lei ;

Zhu, Changqing .

ANALYTICAL CHEMISTRY, 2011, 83 (04) :1401-1407

[28] Target-induced strand release and thionine-decorated gold nanoparticle amplification labels for sensitive electrochemical aptamer-based sensing of small molecules [J].

Yang, Cuiyun ;

Wang, Qiong ;

Xiang, Yun ;

Yuan, Ruo ;

Chai, Yaqin .

SENSORS AND ACTUATORS B-CHEMICAL, 2014, 197 :149-154

[29] Targeting cancer cells with biotin-dendrimer conjugates [J].

Yang, Wenjun ;

Cheng, Yiyun ;

Xu, Tongwen ;

Wang, Xueyuan ;

Wen, Long-ping .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (02) :862-868

[30] Synthesis of differently sized silver nanoparticles on a screen-printed electrode sensitized with a nanocomposites consisting of reduced graphene oxide and cerium(IV) oxide for nonenzymatic sensing of hydrogen peroxide [J].

Yao, Zufu ;

Yang, Xin ;

Wu, Feng ;

Wu, Weilin ;

Wu, Fangping .

MICROCHIMICA ACTA, 2016, 183 (10) :2799-2806

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