Achievement of behavioral efficacy and improved potency in new heterocyclic analogs of benzofuran H3 antagonists

被引：5

作者：

Cowart, M ^{[1
]}

Faghih, R ^{[1
]}

Gfesser, G ^{[1
]}

Curtis, M ^{[1
]}

Sun, M ^{[1
]}

Zhao, C ^{[1
]}

Bennani, Y ^{[1
]}

Wetter, J ^{[1
]}

Marsh, K ^{[1
]}

Miller, TR ^{[1
]}

Krueger, K ^{[1
]}

Pan, JB ^{[1
]}

Drescher, K ^{[1
]}

Fox, GB ^{[1
]}

Esbenshade, TA ^{[1
]}

Hancock, AA ^{[1
]}

机构：

[1] Abbott Labs, Dept R4MN, Abbott Pk, IL 60064 USA

来源：

INFLAMMATION RESEARCH | 2005年 / 54卷 / Suppl 1期

关键词：

D O I：

10.1007/s00011-004-0411-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：S25 / S26

页数：2

共 7 条

[1] The physiology of brain histamine [J].

Brown, RE ;

Stevens, DR ;

Haas, HL .

PROGRESS IN NEUROBIOLOGY, 2001, 63 (06) :637-672

[2] A new class of potent non-imidazole H3 antagonists:: 2-aminoethylbenzofurans [J].

Cowart, M ;

Pratt, JK ;

Stewart, AO ;

Bennani, YL ;

Esbenshade, TA ;

Hancock, AA .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (03) :689-693

[3]

COWART MD, 2002, Patent No. 20020169188

[4]

ESBENSHADE TA, CHARACTERIZATION HIS

[5] Cognition enhancing effects of novel H3 receptor (H3R) antagonists in several animal models [J].

Fox, GB ;

Pan, JB ;

Lewis, AM ;

Browman, KE ;

Komater, VA ;

Buckley, MJ ;

Curzon, P ;

Radek, RJ ;

Faghih, R ;

Esbenshade, TA ;

Cowart, MD ;

Decker, MW ;

Hancock, AA .

INFLAMMATION RESEARCH, 2004, 53 (Suppl 1) :S49-S50

[6] Two novel and selective nonimidazole H3 receptor antagonists A-304121 and A-317920:: II.: In vivo behavioral and neurophysiological characterization [J].

Fox, GB ;

Pan, JB ;

Radek, RJ ;

Lewis, AM ;

Bitner, RS ;

Esbenshade, TA ;

Faghih, R ;

Bennani, YL ;

Williams, M ;

Yao, BB ;

Decker, MW ;

Hancock, AA .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 305 (03) :897-908

[7] Recent advances in histamine H3/H4 receptor ligands [J].

Stark, H .

EXPERT OPINION ON THERAPEUTIC PATENTS, 2003, 13 (06) :851-865

← 1 →