Detection of Favorable Oral Cephalosporin-Clavulanate Interactions by In Vitro Disk Approximation Susceptibility Testing of Extended-Spectrum- Beta-Lactamase-Producing Members of the Enterobacteriaceae

被引：16

作者：

Campbell, Jennifer D. ^{[2
,3
,4
]}

Lewis, James S., II ^{[3
,4
,5
]}

McElmeel, M. Leticia ^{[1
]}

Fulcher, Letitia C. ^{[1
]}

Jorgensen, James H. ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Pathol, San Antonio, TX 78229 USA

[2] S Texas Vet Healthcare Syst, San Antonio, TX USA

[3] Univ Texas Austin, Coll Pharm, Pharmacotherapy Div, Austin, TX 78712 USA

[4] Univ Texas Hlth Sci Ctr San Antonio, Pharmacotherapy Educ & Res Ctr, San Antonio, TX 78229 USA

[5] Univ Hlth Syst, San Antonio, TX USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 03期

关键词：

PHARMACOKINETICS; COMBINATION; ACID; VOLUNTEERS; EMERGENCE;

D O I：

10.1128/JCM.06248-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Extended-spectrum-beta-lactamase (ESBL)-producing members of the Enterobacteriaceae are often resistant to multiple drug classes, making therapy of urinary infections with oral antibiotics difficult. Previously it was shown that amoxicillin-clavulanate can provide clavulanate inhibition of ESBLs and protect an oral cephalosporin present in combination when tested by broth microdilution. This study has shown that disk approximation testing could detect favorable cephalosporin-clavulanate interactions among a group of 101 previously characterized members of the Enterobacteriaceae with CTX-M, SHV, or TEM ESBLs.

引用

页码：1023 / 1026

页数：4

共 19 条

[1]

[Anonymous], 2011, Performance standards for antimicrobial disk susceptibility tests

[2]

approved standard M2-A11, V11th

[3] The CTX-M β-lactamase pandemic [J].

Canton, Rafael ;

Coque, Teresa M. .

CURRENT OPINION IN MICROBIOLOGY, 2006, 9 (05) :466-475

[4] First report of the emergence of CTX-M-Type extended-spectrum β-lactamases (ES-BLs) as the predominant ESBL isolated in a US health care Systemdel [J].

Lewis, James S., II ;

Herrera, Monica ;

Wickes, Brian ;

Patterson, Jan E. ;

Jorgensen, James H. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (11) :4015-4021

[5]

Miller Linda A., 2001, Current Opinion in Pharmacology, V1, P451, DOI 10.1016/S1471-4892(01)00079-0

[6] PHARMACOKINETICS OF CLAVULANIC ACID, GIVEN IN COMBINATION WITH AMOXYCILLIN, IN VOLUNTEERS [J].

NILSSONEHLE, I ;

FELLNER, H ;

HEDSTROM, SA ;

NILSSONEHLE, P ;

SJOVALL, J .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1985, 16 (04) :491-498

[7] Extended-spectrum β-lactamase producing Escherichia coli: changing epidemiology and clinical impact [J].

Oteo, Jesus ;

Perez-Vazquez, Maria ;

Campos, Jose .

CURRENT OPINION IN INFECTIOUS DISEASES, 2010, 23 (04) :320-326

[8]

Pal R B, 2008, J Indian Med Assoc, V106, P545

[9] Extended-spectrum β-lactamases:: a clinical update [J].

Paterson, DL ;

Bonomo, RA .

CLINICAL MICROBIOLOGY REVIEWS, 2005, 18 (04) :657-+

[10] Emergence of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) in the community [J].

Pitout, JDD ;

Nordmann, P ;

Laupland, KB ;

Poirel, L .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (01) :52-59

← 1 2 →