Microwave-Assisted Synthesis of New Quinazolinone and (dihydroquinazolinylphenyl)oxazolone Derivatives

被引：8

作者：

Fozooni, Samieh ^{[1
]}

Firoozi, Halime ^{[2
]}

机构：

[1] Shahid Bahonar Univ, Min Engn Dept, Higher Educ Complex Zarand, Kerman 7761156391, Iran

[2] Payame Noor Univ, Dept Chem, Tehran 193954697, Iran

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2015年 / 51卷 / 04期

关键词：

oxazolone; quinazolinone; microwave irradiation; synthesis; SOLVENT-FREE CONDITIONS; ONE-POT; FACILE SYNTHESIS; EFFICIENT; ACID; CATALYST; 2,3-DIHYDRO-4(1H)-QUINAZOLINONES; 2,3-DIHYDROQUINAZOLIN-4(1H)-ONES; QUINAZOLIN-4(3H)-ONES; CYTOTOXICITY;

D O I：

10.1007/s10593-015-1705-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,3-Dihydroquinazolin-4(1H)-one derivatives were synthesized via a one-pot, three-component reaction of isatoic anhydride and an aromatic aldehyde with 4-aminohippuric acid, catalyzed by acetic acid. After completion of the reaction, the corresponding products were reacted with an aromatic aldehyde, acetic anhydride, and sodium acetate to yield oxazolone derivatives. The reactions were carried out under microwave irradiation and reflux.

引用

页码：340 / 345

页数：6

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