The evolution of thienopyridine therapy - Clopidogrel duration, diabetes, and drug-eluting stents

被引:12
作者
Choi, Seung-Hyuk [1 ,2 ]
Prasad, Anand [1 ,2 ]
Tsimikas, Sotirios [1 ,2 ]
机构
[1] Univ Calif San Diego, Vasc Med Program, Div Cardiol, La Jolla, CA 92093 USA
[2] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med, Seoul, South Korea
关键词
D O I
10.1016/j.jacc.2008.03.017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The widespread clinical application of coronary stents was paralleled by another fundamental advance in adjunctive medical therapy, namely the recognition of the critical role of the platelet in stent thrombosis. During the early development of bare-metal stents (BMS), the use of prolonged heparin infusion, dextran, aspirin, dipyridamole, and warfarin remained suboptimal in preventing acute and subacute stent thrombosis. The addition of thienopyridines to aspirin, along with optimal stent deployment techniques, had reduced the incidence of stent thrombosis to an acceptably low level (1% to 2%).
引用
收藏
页码:2228 / 2229
页数:2
相关论文
共 19 条
[1]   Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment [J].
Airoldi, Flavio ;
Colombo, Antonio ;
Morici, Nuccia ;
Latib, Azeem ;
Cosgrave, John ;
Buellesfeld, Lutz ;
Bonizzoni, Erminio ;
Carlino, Mauro ;
Gerckens, Ulrich ;
Godino, Cosmo ;
Melzi, Gloria ;
Michev, Iassen ;
Montorfano, Matteo ;
Sangiorgi, Giuseppe Massimo ;
Qasim, Asif ;
Chieffo, Alaide ;
Briguori, Carlo ;
Grube, Eberhard .
CIRCULATION, 2007, 116 (07) :745-754
[2]   Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease [J].
Angiolillo, Dominick J. ;
Bernardo, Esther ;
Sabate, Manel ;
Jimenez-Quevedo, Pilar ;
Costa, Marco A. ;
Palazuelos, Jorge ;
Hernandez-Antolin, Rosana ;
Moreno, Raul ;
Escaned, Javier ;
Alfonso, Fernando ;
Banuelos, Camino ;
Guzman, Luis A. ;
Bass, Theodore A. ;
Macaya, Carlos ;
Fernandez-Ortiz, Antonio .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 50 (16) :1541-1547
[3]   Outcomes and complications associated with off-label and untested use of drug-eluting stents [J].
Beohar, Nirat ;
Davidson, Charles J. ;
Kip, Kevin E. ;
Goodreau, Lynne ;
Aslanidou Vlachos, Helen ;
Meyers, Sheridan N. ;
Benzuly, Keith H. ;
Flaherty, James D. ;
Ricciardi, Mark J. ;
Bennett, Charles L. ;
Williams, David O. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 297 (18) :1992-2000
[4]   Long-term outcomes by clopidogrel duration and stent type in a diabetic population with de novo coronary artery lesions [J].
Brar, Somjot S. ;
Kim, John ;
Brar, Simerjeet K. ;
Zadegan, Ray ;
Ree, Michael ;
Liu, In-Lu A. ;
Mansukhani, Prakash ;
Aharonian, Vicken ;
Hyett, Ric ;
Shen, Albert Yuh-Jer .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 51 (23) :2220-2227
[5]   Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation [J].
Eisenstein, Eric L. ;
Anstrom, Kevin J. ;
Kong, David F. ;
Shaw, Linda K. ;
Tuttle, Robert H. ;
Mark, Daniel B. ;
Kramer, Judith M. ;
Harrington, Robert A. ;
Matchar, David B. ;
Kandzari, David E. ;
Peterson, Eric D. ;
Schulman, Kevin A. ;
Califf, Robert M. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 297 (02) :159-168
[6]   Prevention of premature ditscontinuation of dual antiplatelet therapy in patients with coronary artery stents [J].
Grines, Cindy L. ;
Bonow, Robert O. ;
Casey, Donald E., Jr. ;
Gardner, Timothy J. ;
Lockhart, Peter B. ;
Moliterno, David J. ;
O'Gara, Patrick ;
Whitlow, Patrick .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 49 (06) :734-739
[7]   Drug-eluting compared with bare-metal coronary stents among elderly patients [J].
Groeneveld, Peter W. ;
Matta, Mary Anne ;
Greenhut, Alexis P. ;
Yang, Feifei .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 51 (21) :2017-2024
[8]   Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents [J].
Iakovou, I ;
Schmidt, T ;
Bonizzoni, E ;
Ge, L ;
Sangiorgi, GM ;
Stankovic, G ;
Airoldi, F ;
Chieffo, A ;
Montorfano, M ;
Carlino, M ;
Michev, I ;
Corvaja, N ;
Briguori, C ;
Gerckens, U ;
Grube, E ;
Colombo, A .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 293 (17) :2126-2130
[9]   Stent thrombosis, myocardial infarction, and death after drug-eluting and bare-metal Stent coronary interventions [J].
Jensen, Lisette Okkels ;
Maeng, Michael ;
Kaltoft, Anne ;
Thayssen, Per ;
Hansen, Hans Henrik Tilsted ;
Bottcher, Morten ;
Lassen, Jens Flensted ;
Krussel, Lars Romer ;
Rasmussen, Klaus ;
Hansen, Knud Noerregaard ;
Pedersen, Lars ;
Johnsen, Soeren Paaske ;
Soerensen, Henrik Toft ;
Thuesen, Leif .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 50 (05) :463-470
[10]   Pathology of drug-eluting stents in humans - Delayed healing and late thrombotic risk [J].
Joner, Michael ;
Finn, Aloke V. ;
Farb, Andrew ;
Mont, Erik K. ;
Kolodgie, Frank D. ;
Ladich, Elena ;
Kutys, Robert ;
Skorija, Kristi ;
Gold, Herman K. ;
Virmani, Renu .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (01) :193-202