Performance of the MGIT TBc Identification Test and Meta-Analysis of MPT64 Assays for Identification of the Mycobacterium tuberculosis Complex in Liquid Culture

被引：38

作者：

Brent, Andrew J. ^{[1
,2
]}

Mugo, Daisy ^{[1
]}

Musyimi, Robert ^{[1
]}

Mutiso, Agnes ^{[1
]}

Morpeth, Susan ^{[1
,4
]}

Levin, Michael ^{[3
]}

Scott, J. Anthony G. ^{[1
,4
]}

机构：

[1] KEMRI Wellcome Trust Res Programme, Kilifi 80108, Kenya

[2] Univ London Imperial Coll Sci Technol & Med, Wellcome Trust Ctr Clin Trop Med, London, England

[3] Univ London Imperial Coll Sci Technol & Med, Dept Pediat, London, England

[4] Univ Oxford, Nuffield Dept Clin Med, Oxford, England

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 12期

基金：

比尔及梅琳达.盖茨基金会; 英国惠康基金;

关键词：

CAPILIA TB; RAPID IDENTIFICATION; IMMUNOCHROMATOGRAPHIC ASSAY; CONFIRMATION; SYSTEM; COST; KIT;

D O I：

10.1128/JCM.05995-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Rapid MPT64-based immunochromatographic tests (MPT64 ICTs) have been developed to detect Mycobacterium tuberculosis complex (MTBC) in culture. We demonstrated the noninferiority of one commercial MTP64 ICT, the MGIT TBc identification (TBcID) test, to GenoType line probe assays for MTBC identification in positive MGIT cultures. Meta-analysis of MPT64 ICT performance for identification of MTBC in liquid culture confirmed similar very high sensitivities and specificities for all three commercial MPT64 assays for which sufficient data were available.

引用

页码：4343 / 4346

页数：4

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