Chronic Q Fever in a Renal Transplant Recipient: A Case Report

被引：13

作者：

Godinho, I. ^{[1
]}

Nogueira, E. L. ^{[1
]}

Santos, C. M. ^{[2
]}

Paulo, S. E. ^{[2
]}

Fortes, A. ^{[1
]}

Guerra, J. O. ^{[1
]}

Gomes da Costa, A. ^{[1
]}

机构：

[1] Hosp Santa Maria, Ctr Hosp Lisboa Norte, Nephrol & Renal Transplantat Dept, P-1649035 Lisbon, Portugal

[2] Hosp Santa Maria, Ctr Hosp Lisboa Norte, Dept Infect Dis, P-1649035 Lisbon, Portugal

来源：

TRANSPLANTATION PROCEEDINGS | 2015年 / 47卷 / 04期

关键词：

DIAGNOSTIC-CRITERIA; PARTURIENT CAT; ENDOCARDITIS; OUTBREAK; NETHERLANDS; INFECTION; PNEUMONIA; FRANCE;

D O I：

10.1016/j.transproceed.2015.03.022

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Q fever is a zoonosis caused by Coxiella burnetii that presents with a wide spectrum of acute and chronic manifestations. Progression to chronic Q fever is frequently associated with valve and vascular prosthesis, aneurisms, pregnancy, immunosuppression, and advanced chronic kidney disease. We present a case of a kidney transplant recipient with persistent fever of unknown origin, negative blood cultures, anemia, and increased erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Q fever serological tests were suggestive of chronic Q fever and the patient was diagnosed with probable chronic Q fever according to the Dutch Fever Consensus Group Guidelines. Initiation of doxycycline 200 mg/d and hydroxychloroquine 600 mg/d resulted in clinical remission. Chronic Q fever is a high-morbidity and -mortality disease if untreated and special attention has to be given to high-risk patients, such as kidney transplant recipients.

引用

页码：1045 / 1047

页数：3

共 31 条

[1]

[Anonymous], TIJDSCHRIFT INFECTIE

[2] Localizing chronic Q fever: a challenging query [J].

Barten, Dennis G. ;

Delsing, Corine E. ;

Keijmel, Stephan P. ;

Sprong, Tom ;

Timmermans, Janneke ;

Oyen, Wim J. G. ;

Nabuurs-Franssen, Marrigje H. ;

Bleeker-Rovers, Chantal P. .

BMC INFECTIOUS DISEASES, 2013, 13

[3]

Bossi P., 2004, Euro Surveill, V9, P1

[4] Coxiella burnetii infection of aortic aneurysms grafts:: report of 30 new cases and evaluation or vascular of outcome [J].

Botelho-Nevers, E. ;

Fournier, P.-E. ;

Richet, H. ;

Fenollar, F. ;

Lepidi, H. ;

Foucault, C. ;

Branchereau, A. ;

Piquet, P. ;

Maurin, M. ;

Raoult, D. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2007, 26 (09) :635-640

[5] CHRONIC Q-FEVER - 92 CASES FROM FRANCE, INCLUDING 27 CASES WITHOUT ENDOCARDITIS [J].

BROUQUI, P ;

DUPONT, HT ;

DRANCOURT, M ;

BERLAND, Y ;

ETIENNE, J ;

LEPORT, C ;

GOLDSTEIN, F ;

MASSIP, P ;

MICOUD, M ;

BERTRAND, A ;

RAOULT, D .

ARCHIVES OF INTERNAL MEDICINE, 1993, 153 (05) :642-648

[6]

Delsing CE, 2010, NETH J MED, V68, P382

[7] Molecular detection of Coxiella burnetti in the sera of patients with Q fever endocarditis or vascular infection [J].

Fenollar, F ;

Fournier, PE ;

Raoult, D .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (11) :4919-4924

[8] Risks factors and prevention of Q fever endocarditis [J].

Fenollar, F ;

Fournier, PE ;

Carrieri, MP ;

Habib, G ;

Messana, T ;

Raoult, D .

CLINICAL INFECTIOUS DISEASES, 2001, 33 (03) :312-316

[9] Modification of the diagnostic criteria proposed by the duke endocarditis service to permit improved diagnosis of Q fever endocarditis [J].

Fournier, PE ;

Casalta, JP ;

Habib, G ;

Messana, T ;

Raoult, D .

AMERICAN JOURNAL OF MEDICINE, 1996, 100 (06) :629-633

[10] Q Fever in France, 1985-2009 [J].

Frankel, Diane ;

Richet, Herve ;

Renvoise, Aurelie ;

Raoult, Didier .

EMERGING INFECTIOUS DISEASES, 2011, 17 (03) :350-356

← 1 2 3 4 →