A highly selective and ultrasensitive ratiometric fluorescent probe for peroxynitrite and its two-photon bioimaging applications

被引：44
作者：
Wang, Zuokai [1 ]
Wu, Liu [1 ]
Wang, Yawei [1 ]
Zhang, Meng [1 ]
Zhao, Ziyang [1 ]
Liu, Caiyun [1 ]
Duan, Qingxia [1 ]
Jia, Pan [1 ]
Zhu, Baocun [1 ]
机构：
[1] Univ Jinan, Shandong Prov Engn Technol Res Ctr Ecol Carbon Si, Sch Resources & Environm, Jinan 250022, Shandong, Peoples R China
来源：
ANALYTICA CHIMICA ACTA | 2019年 / 1049卷
基金：
中国国家自然科学基金;
关键词：
Fluorescent probe; Peroxynitrite (ONOO-); Ratiometric detection; Hydroxynaphthalimide; Two-photon bioimaging; DRUG-INDUCED HEPATOTOXICITY; ENDOGENOUS PEROXYNITRITE; LIVING CELLS; HYDROGEN-PEROXIDE; FAST-RESPONSE; BORONATE OXIDATION; MITOCHONDRIA; VISUALIZATION; CHEMISTRY; NITROXYL;
D O I：
10.1016/j.aca.2018.05.064
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this work, taking full advantage of the intramolecular charge transfer (ICT) mechanism, a hydroxynaphthalimide-based ratiometric two-photon fluorescent probe RTP-PN was synthesized to detect ONOO-. Probe RTP-PN could accurately detect ONOO- in the range of 1.4 nM-1.4 mM with the detection limit of 1.4 nM by a ratiometric fluorescence spectroscopy method. Additionally, probe RTP-PN exhibited an ultrafast response for ONOO- than other various species including H2O2 and ClO-. Finally, probe RTP-PN was successfully adopted to detect intracellular ONOO- by the two-photon excitation microscopy. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码：219 / 225
页数：7
相关论文
共 57 条
[1]  
Chan J, 2012, NAT CHEM, V4, P973, DOI [10.1038/NCHEM.1500, 10.1038/nchem.1500]
[2]   Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species [J].
Chen, Xiaoqiang ;
Wang, Fang ;
Hyun, Ji Young ;
Wei, Tingwen ;
Qiang, Jian ;
Ren, Xintong ;
Shin, Injae ;
Yoon, Juyoung .
CHEMICAL SOCIETY REVIEWS, 2016, 45 (10) :2976-3016
[3]   Investigation of Drug-Induced Hepatotoxicity and Its Remediation Pathway with Reaction-Based Fluorescent Probes [J].
Cheng, Dan ;
Xu, Wang ;
Yuan, Lin ;
Zhang, Xiaobing .
ANALYTICAL CHEMISTRY, 2017, 89 (14) :7693-7700
[4]   Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe [J].
Cheng, Dan ;
Pan, Yue ;
Wang, Lu ;
Zeng, Zebing ;
Yuan, Lin ;
Zhang, Xiaobing ;
Chang, Young-Tae .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (01) :285-292
[5]   A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A [J].
Dai, Zi-Ru ;
Ge, Guang-Bo ;
Feng, Lei ;
Ning, Jing ;
Hu, Liang-Hai ;
Jin, Qiang ;
Wang, Dan-Dan ;
Lv, Xia ;
Dou, Tong-Yi ;
Cui, Jing-Nan ;
Yang, Ling .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (45) :14488-14495
[6]   A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells [J].
Dickinson, Bryan C. ;
Huynh, Calvin ;
Chang, Christopher J. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (16) :5906-5915
[7]   Chemistry of peroxynitrites as compared to peroxynitrates [J].
Goldstein, S ;
Lind, J ;
Merényi, G .
CHEMICAL REVIEWS, 2005, 105 (06) :2457-2470
[8]   A highly selective water-soluble optical probe for endogenous peroxynitrite [J].
Hou, Ji-Ting ;
Yang, Jin ;
Li, Kun ;
Liao, Ye-Xin ;
Yu, Kang-Kang ;
Xie, Yong-Mei ;
Yu, Xiao-Qi .
CHEMICAL COMMUNICATIONS, 2014, 50 (69) :9947-9950
[9]   Oxidative stress and nitration in neurodegeneration: Cause, effect, or association? [J].
Ischiropoulos, H ;
Beckman, JS .
JOURNAL OF CLINICAL INVESTIGATION, 2003, 111 (02) :163-169
[10]   FRET-Based Mito-Specific Fluorescent Probe for Ratiometric Detection and Imaging of Endogenous Peroxynitrite: Dyad of Cy3 and Cy5 [J].
Jia, Xiaotong ;
Chen, Qiangqiang ;
Yang, Yingfang ;
Tang, Yao ;
Wang, Rui ;
Xu, Yufang ;
Zhu, Weiping ;
Qian, Xuhong .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (34) :10778-10781
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