Factors leading oncologists to refer elderly cancer patients for geriatric assessment

被引:18
作者
Lazarovici, Celine [1 ]
Khodabakhshi, Reza [2 ,4 ]
Leignel, Delphine [2 ]
Fabre-Guillevin, Elizabeth [3 ]
Minard, Aurelien [1 ]
Gisselbrecht, Mathilde [1 ]
机构
[1] HEGP, AP HP, Dept Geriatr, F-75015 Paris, France
[2] HEGP, Dept Radiotherapy, F-75015 Paris, France
[3] HEGP, Dept Med Oncol, F-75015 Paris, France
[4] Fayazbakhsh Hosp, Dept Radiooncol, Tehran, Iran
关键词
Geriatric oncology; Elderly; Cancer; Frailty; CGA; MINI-MENTAL-STATE; FUNCTIONAL STATUS; DEPRESSION; ILLNESS; CHEMOTHERAPY; COMORBIDITY; MANAGEMENT;
D O I
10.1016/j.jgo.2011.03.001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objectives: We characterized elderly cancer patients referred to an oncogeriatric unit and sought factors warranting referral for geriatric assessment before or during cancer therapy. Materials and methods: We reviewed the files of all consecutive elderly patients seen from October 2006 to April 2008 in our primary-care oncogeriatric unit. All subjects had a comprehensive geriatric assessment. Patients evaluated before oncologic decision-making were compared to those evaluated after cancer therapy had started. Results: We studied 65 patients with a median age of 82.4 years (range 71-95). The most frequent malignancies were breast (29.0%), lung (24.6%) and colorectal tumors (7.6%). Thirty-nine patients (60%) had metastatic disease. One-quarter of patients had one or more disabilities on the Activities of Daily Living scale, more than half (53.8%) were classified as. dependent on the Instrumental Activities of Daily Living scale, and nearly half (45.3%) had cognitive dysfunction. Thirty-five patients were evaluated before oncologic decision-making and thirty during cancer treatment. Recent weight loss > 10% (32.3% vs 15.3%; p = 0.031) was more frequent among patients who had a geriatric assessment before cancer therapy. These latter patients were also taking fewer drugs (4.8 vs 6.1; p = 0.036) and were more likely to receive adjusted cancer therapy (41.5% vs 26.1%; p = 0.051). Conclusion: Weight loss was the main feature leading oncologists to refer elderly cancer patients for geriatric assessment. Patients who had a geriatric assessment before oncologic decision-making were more likely to receive adjusted cancer therapy. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:194 / 199
页数:6
相关论文
共 31 条
[1]  
Balducci L, 1997, CANCER, V80, P1317, DOI 10.1002/(SICI)1097-0142(19971001)80:7<1317::AID-CNCR18>3.3.CO
[2]  
2-I
[3]   Cancer and aging - An evolving panorama [J].
Balducci, L ;
Extermann, M .
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 2000, 14 (01) :1-+
[4]   4 INSTRUMENTAL ACTIVITIES OF DAILY LIVING SCORE AS A PREDICTOR OF ONE-YEAR INCIDENT DEMENTIA [J].
BARBERGERGATEAU, P ;
DARTIGUES, JF ;
LETENNEUR, L .
AGE AND AGEING, 1993, 22 (06) :457-463
[5]   Management of Frail and Not-Frail elderly cancer patients in a hospital-based geriatric oncology program [J].
Basso, Umberto ;
Tonti, Singora ;
Bassi, Catia ;
Brunello, Antonella ;
Pasetto, Lara Maria ;
Scaglione, Daniela ;
Falci, Cristina ;
Beda, Manuela ;
Aversa, Savina Maria Luciana ;
Stefani, Micaela ;
Castegnaro, Eugenio ;
Tamellini, Fabio ;
Monfardini, Silvio .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2008, 66 (02) :163-170
[6]   Explicit criteria for determining potentially inappropriate medication use by the elderly - An update [J].
Beers, MH .
ARCHIVES OF INTERNAL MEDICINE, 1997, 157 (14) :1531-1536
[7]  
Bellera C., 2008, Crit Rev Oncol Hematol, V68, P2, DOI [10.1016/S1040-8428(08)70042-8, DOI 10.1016/S1040-8428(08)70042-8]
[8]   A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION [J].
CHARLSON, ME ;
POMPEI, P ;
ALES, KL ;
MACKENZIE, CR .
JOURNAL OF CHRONIC DISEASES, 1987, 40 (05) :373-383
[9]  
Clement JP, 1997, ENCEPHALE, V23, P91
[10]   SERUM-ALBUMIN LEVEL AND PHYSICAL-DISABILITY AS PREDICTORS OF MORTALITY IN OLDER PERSONS [J].
CORTI, MC ;
GURALNIK, JM ;
SALIVE, ME ;
SORKIN, JD .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 272 (13) :1036-1042