End-tidal CO2 as a function of tidal volume in mechanically ventilated infants

被引：0
作者：
Greer, KJ [1 ]
Bowen, WA [1 ]
Krauss, AN [1 ]
机构：
[1] New York Presbyterian Hosp, Weill Cornell Med Ctr, Dept Pediat, Perinatol Ctr, New York, NY 10021 USA
来源：
AMERICAN JOURNAL OF PERINATOLOGY | 2003年 / 20卷 / 08期
关键词：
mechanical ventilation; preterm infants; end-tidal CO2;
D O I：
暂无
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To test the hypothesis that end-tidal CO2 (PETCO2) varies with tidal volume (Vt) in preterm infants. Design: Intervention study, nonrandomized trial. Setting: Neonatal ICU, regional referral center. Subjects: 29 preterm infants 790 to 2135 g in weight requiring mechanical ventilation studied on 73 occasions. Intervention: Measurement of PETCO2 during variations of Vt. Measurement: Statistical correlation of PETCO2 to Vt. Result: PETCO2 is minimal when Vt is either too low or too high. Conclusion: Vt, through its effect on dead space/Vt (Vd/Vt) ratios and arterial-alveolar CO 2 differences, has a significant effect on PETCO2. Observation of PETCO2 across a range of Vt can be used to select an appropriate Vt for preterm infants requiring mechanical ventilation.
引用
收藏
页码：447 / 451
页数：5
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