Quality control of liquid herbal drug preparations: ethanol content and test on methanol and 2-propanol

被引:12
|
作者
Apers, S [1 ]
Van Meenen, E [1 ]
Pieters, L [1 ]
Vlietinck, A [1 ]
机构
[1] Univ Antwerp, Dept Pharmaceut Sci, B-2610 Antwerp, Belgium
关键词
liquid herbal drug preparations; tinctures; liquid extracts; ethanol content; methanol; 2-propanol; quality control;
D O I
10.1016/S0731-7085(03)00302-9
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In the quality control of liquid herbal drug preparations, i.e. tinctures and liquid extracts, the ethanol content is determined and the test on methanol and 2-propanol is performed. Capillary headspace GC/MS methods for both analyses were developed and fully validated. These specific, selective, accurate and precise methods are a fast and fully automated alternative for the laborious methods of the European Pharmacopoeia, since they need no or only simple sample preparation. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:529 / 537
页数:9
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