Strategies for Distinguishing Low-grade Endometrioid and Serous Carcinomas of Endometrium

被引：36
|
作者：
Garg, Karuna [1 ]
Soslow, Robert A. [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
来源：
ADVANCES IN ANATOMIC PATHOLOGY | 2012年 / 19卷 / 01期
关键词：
endometrium; serous carcinomas; endometrioid carcinomas; morphologically ambiguous carcinomas; COMPLEX ATYPICAL HYPERPLASIA; P53 PROTEIN OVEREXPRESSION; BETA-CATENIN; MICROSATELLITE INSTABILITY; PROGNOSTIC-SIGNIFICANCE; IMMUNOHISTOCHEMICAL EXPRESSION; CLINICOPATHOLOGICAL ANALYSIS; MOLECULAR ALTERATIONS; FAVORABLE-PROGNOSIS; PAPILLARY CARCINOMA;
D O I：
10.1097/PAP.0b013e318234ab36
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Distinction between endometrioid and serous carcinomas of the endometrium has important prognostic and therapeutic implications. Misdiagnosing a serous carcinoma as endometrioid can have significant consequences for the patient and pathologist. Although many cases are straightforward and easy to classify, there are occasional problematic cases. This review focuses on strategies that help differentiate between low-grade endometrioid carcinoma and serous carcinoma of the endometrium. We will discuss clinical, morphologic, and immunohistochemical differences between the 2 entities and provide practical tips for practicing pathologists when confronted with this differential diagnosis.
引用
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页码：1 / 10
页数：10
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