Copper(II)-catalyzed oxidative N-nitrosation of secondary and tertiary amines with nitromethane under an oxygen atmosphere

被引:30
作者
Sakai, Norio [1 ]
Sasaki, Minoru [1 ]
Ogiwara, Yohei [1 ]
机构
[1] Tokyo Univ Sci RIKADAI, Fac Sci & Technol, Dept Pure & Appl Chem, Noda, Chiba 2788510, Japan
关键词
MILD CONDITIONS; NEF REACTION; HETEROGENEOUS CONDITIONS; MOLECULAR-OXYGEN; NITRIC-OXIDE; SULFURIC ACID/NANO2; NITROSAMINES; DIOXYGEN; AMIDES; AGENT;
D O I
10.1039/c5cc03675e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The combination of a catalytic amount of Cu(OTf)(2) and less than a stoichiometric amount of 1,8-diazabicyclo[5.4.0] undec-7-ene (DBU) under an O-2 atmosphere effectively promoted the N-nitrosation of both secondary aromatic/aliphatic amines and tertiary aromatic amines with nitromethane (CH3NO2) leading to the preparation of N-nitrosamine derivatives.
引用
收藏
页码:11638 / 11641
页数:4
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