Synthesis, Characterization and Antibacterial Activity of Schiff Bases and their Metal Complexes Derived from 4-Acyl-1-phenyl-3-methyl-2-pyrazolin-5-ones and 2-Amino-4(4′-methylphenyl)thiazole

被引：24
作者：
Thakar, A. S. [1 ]
Singh, K. K. [1 ]
Joshi, K. T. [2 ]
Pancholi, A. M. [2 ]
Pandya, K. S. [3 ]
机构：
[1] Zydus Res Ctr, Ahmadabad 382210, Gujarat, India
[2] Navjivan Sci Coll, Dept Chem, Dahod 389151, India
[3] Sir PT Sci Coll, Modasa 383315, India
来源：
E-JOURNAL OF CHEMISTRY | 2010年 / 7卷 / 04期
关键词：
Pyrazolone; 2-Amino thiazole; Schiff base; Transition metals; Spectroscopy; Antibacterial activity; DIOXOMOLYBDENUM(VI) COMPLEXES; CRYSTAL-STRUCTURE; DERIVATIVES;
D O I：
10.1155/2010/163264
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
4-Acyl-1-phenyl-3-methyl-2-pyrazolin-5-ones condensed with 2-amino-4(4'-methylphenyl)-thiazole to form Schiff base. These Schiff bases from complexes of type ML(2 center dot)2H(2)O (M= Mn, Fe, Co, Ni and Cu). Elemental analysis, magnetic susceptibility, electrical conductance, electronic and Infrared spectral data suggested octahedral structure for the complexes. All the compounds were tested for their antibacterial activity. The result indicates that the growth of the tested organism was inhibited by most of the compounds. These Schiff bases are characterized by elemental analysis, mass spectra, H-1-NMR spectra, C-13 NMR spectra and FT IR spectra.
引用
收藏
页码：1396 / 1406
页数：11
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