Cerebellar liponeurocytoma in two siblings suggests a possible familial predisposition

被引:5
作者
Pikis, Stylianos [1 ]
Fellig, Yakov [2 ]
Margolin, Emil [3 ]
机构
[1] Korgialenio Benakio Red Cross Hosp Athens, Dept Neurosurg, Athens 11526, Greece
[2] Hadassah Hebrew Univ Med Ctr, Dept Pathol, IL-91120 Jerusalem, Israel
[3] Hadassah Hebrew Univ Med Ctr, Dept Neurosurg, POB 12000, IL-91120 Jerusalem, Israel
关键词
Biology; Cerebellar liponeurocytomas; Familial; Inheritance;
D O I
10.1016/j.jocn.2016.04.004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
There is limited data on the genetic origin and natural history of cerebellar liponeurocytoma. To the best of our knowledge there has been only one report of a familial presentation of this rare entity. We report a 72-year-old female with a posterior fossa tumor presenting with progressive cerebellar signs and symptoms. The patient underwent total tumor resection via an uncomplicated sub-occipital craniotomy. Histopathologic examination was diagnostic for cerebellar liponeurocytoma. Her sister was previously treated for a similar tumor. Our report provides further evidence for the possible existence of a hereditary abnormality predisposing afflicted families to cerebellar liponeurocytoma development. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:154 / 156
页数:3
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