Congenital infections with human herpesvirus 6

被引：50

作者：

Adams, O

Krempe, C

Kögler, G

Wernet, P

Scheid, A

机构：

[1] Univ Dusseldorf, Inst Med Mikrobiol & Virol, D-40225 Dusseldorf, Germany

[2] Univ Dusseldorf, Bone Marrow Donor Ctr, Eurocord Bank Germany, Dusseldorf, Germany

来源：

JOURNAL OF INFECTIOUS DISEASES | 1998年 / 178卷 / 02期

关键词：

D O I：

10.1086/517470

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cord blood DNA was tested for the presence of human herpesvirus 6 (HHV-6) DNA by the polymerase chain reaction. Specific DNA could be detected in the specimens of 5 (1.6%) of 305 babies born to ostensibly healthy mothers, indicating that intrauterine infection had occurred. These transmissions would not have been detected by serologic methods, because no specific IgM antibody could be found in the fetal sera. These results indicate that, in addition to infections acquired in early childhood, congenital infections may account for the HHV-6 seropositivity in children.

引用

收藏

页码：544 / 546

页数：3

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