Antibiotic-Resistant Infections and Treatment Challenges in the Immunocompromised Host

被引：21

作者：

Dumford, Donald M., III ^{[1
,2
]}

Skalweit, Marion ^{[3
,4
]}

机构：

[1] Akron Gen Med Ctr, 1 Akron Gen Way, Akron, OH 44302 USA

[2] Northeast Ohio Med Univ, 4209 St Rt 44,POB 95, Rootstown, OH 44272 USA

[3] Louis Stokes Cleveland Dept Vet Affairs, 10701 East Blvd 111 W, Cleveland, OH 44106 USA

[4] Case Western Reserve Univ, Sch Med, 2109 Adelbert Rd, Cleveland, OH 44106 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2016年 / 30卷 / 02期

关键词：

MDRO; Immunocompromise; HIV/AIDS; Organ transplant recipients; Infection; SOLID-ORGAN TRANSPLANT; BLOOD-STREAM INFECTIONS; GRAM-NEGATIVE BACILLI; LACTAMASE-PRODUCING ENTEROBACTERIACEAE; STAPHYLOCOCCUS-AUREUS COLONIZATION; PSEUDOMONAS-AERUGINOSA BACTEREMIA; ACINETOBACTER-BAUMANNII INFECTION; SPECTRUM BETA-LACTAMASES; PATIENTS-RISK-FACTORS; CANCER-PATIENTS;

D O I：

10.1016/j.idc.2016.02.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This article reviews antibiotic resistance and treatment of bacterial infections in the growing number of patients who are immunocompromised: solid organ transplant recipients, the neutropenic host, and persons with human immunodeficiency virus and AIDS. Specific mechanisms of resistance in both gram-negative and gram-positive bacteria, as well as newer treatment options are addressed elsewhere, and are only briefly discussed in the context of the immunocompromised host.

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页码：465 / +

页数：26

相关论文

共 116 条

[71] Septicaemia in a population-based HIV clinical cohort in rural Uganda, 1996-2007: incidence, aetiology, antimicrobial drug resistance and impact of antiretroviral therapy [J].

Mayanja, B. N. ;

Todd, J. ;

Hughes, P. ;

Van der Paal, L. ;

Mugisha, J. O. ;

Atuhumuza, E. ;

Tabuga, P. ;

Maher, D. ;

Grosskurth, H. .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2010, 15 (06) :697-705

[72]

Mebis J, 2010, Infect Drug Resist, V3, P53

[73] Prevalence of multidrug-resistant gram-negative bacilli producing extended-spectrum β-lactamases (ESBLs) and ESBL genes in solid organ transplant recipients [J].

Men, T. -Y. ;

Wang, J. -N. ;

Li, H. ;

Gu, Y. ;

Xing, T. -H. ;

Peng, Z. -H. ;

Zhong, L. .

TRANSPLANT INFECTIOUS DISEASE, 2013, 15 (01) :14-21

[74] Bacteria causing bacteremia in pediatric cancer patients presenting with febrile neutropenia-species distribution and susceptibility patterns [J].

Miedema, Karin G. E. ;

Winter, Rik H. L. J. ;

Ammann, Roland A. ;

Droz, Sara ;

Spanjaard, Lodewijk ;

de Bont, Eveline S. J. M. ;

Kamps, Willem A. ;

van de Wetering, Marianne D. ;

Tissing, Wim J. E. .

SUPPORTIVE CARE IN CANCER, 2013, 21 (09) :2417-2426

[75]

Mikulska M, 2015, CURR DRUG TARGETS

[76] Aetiology and resistance in bacteraemias among adult and paediatric haematology and cancer patients [J].

Mikulska, Malgorzata ;

Viscoli, Claudio ;

Orasch, Christina ;

Livermore, David M. ;

Averbuch, Diana ;

Cordonnier, Catherine ;

Akova, Murat .

JOURNAL OF INFECTION, 2014, 68 (04) :321-331

[77] CTX-M and TEM as Predominant Types of Extended Spectrum β-Lactamases Among Serratia marcescens Isolated From Solid Organ Recipients [J].

Mlynarczyk, A. ;

Szymanek, K. ;

Sawicka-Grzelak, A. ;

Pazik, J. ;

Buczkowska, T. ;

Durlik, M. ;

Lagiewska, B. ;

Pacholczyk, M. ;

Chmura, A. ;

Paczek, L. ;

Mlynarczyk, G. .

TRANSPLANTATION PROCEEDINGS, 2009, 41 (08) :3253-3255

[78] Resistance to Carbapenems Among Pseudomonas aeruginosa Isolated From Patients of Transplant Wards [J].

Mlynarczyk, G. ;

Sawicka-Grzelak, A. ;

Szymanek, K. ;

Buczkowska, T. ;

Pazik, J. ;

Durlik, M. ;

Pacholczyk, M. ;

Lagiewska, B. ;

Chmura, A. ;

Paczek, L. ;

Mlynarczyk, A. .

TRANSPLANTATION PROCEEDINGS, 2009, 41 (08) :3258-3260

[79] Third generation cephalosporin resistant Enterobacteriaceae and multidrug resistant gram-negative bacteria causing bacteremia in febrile neutropenia adult cancer patients in Lebanon, broad spectrum antibiotics use as a major risk factor, and correlation with poor prognosis [J].

Moghnieh, Rima ;

Estaitieh, Nour ;

Mugharbil, Anas ;

Jisr, Tamima ;

Abdallah, Dania I. ;

Ziade, Fouad ;

Sinno, Loubna ;

Ibrahim, Ahmad .

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2015, 5

[80] Recent changes in bacteremia in patients with cancer: a systematic review of epidemiology and antibiotic resistance [J].

Montassier, E. ;

Batard, E. ;

Gastinne, T. ;

Potel, G. ;

de La Cochetiere, M. F. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2013, 32 (07) :841-850

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