Antibiotic-Resistant Infections and Treatment Challenges in the Immunocompromised Host

被引:21
作者
Dumford, Donald M., III [1 ,2 ]
Skalweit, Marion [3 ,4 ]
机构
[1] Akron Gen Med Ctr, 1 Akron Gen Way, Akron, OH 44302 USA
[2] Northeast Ohio Med Univ, 4209 St Rt 44,POB 95, Rootstown, OH 44272 USA
[3] Louis Stokes Cleveland Dept Vet Affairs, 10701 East Blvd 111 W, Cleveland, OH 44106 USA
[4] Case Western Reserve Univ, Sch Med, 2109 Adelbert Rd, Cleveland, OH 44106 USA
关键词
MDRO; Immunocompromise; HIV/AIDS; Organ transplant recipients; Infection; SOLID-ORGAN TRANSPLANT; BLOOD-STREAM INFECTIONS; GRAM-NEGATIVE BACILLI; LACTAMASE-PRODUCING ENTEROBACTERIACEAE; STAPHYLOCOCCUS-AUREUS COLONIZATION; PSEUDOMONAS-AERUGINOSA BACTEREMIA; ACINETOBACTER-BAUMANNII INFECTION; SPECTRUM BETA-LACTAMASES; PATIENTS-RISK-FACTORS; CANCER-PATIENTS;
D O I
10.1016/j.idc.2016.02.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This article reviews antibiotic resistance and treatment of bacterial infections in the growing number of patients who are immunocompromised: solid organ transplant recipients, the neutropenic host, and persons with human immunodeficiency virus and AIDS. Specific mechanisms of resistance in both gram-negative and gram-positive bacteria, as well as newer treatment options are addressed elsewhere, and are only briefly discussed in the context of the immunocompromised host.
引用
收藏
页码:465 / +
页数:26
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