Bilateral cerebral hemispheric infarction associated with sildenafil citrate (Viagra®) use

被引：15
作者：
Kim, K. -K. [1 ]
Kim, D. G. [1 ]
Ku, Y. H. [1 ]
Lee, Y. J. [2 ]
Kim, W. -C. [1 ]
Kim, O. J. [1 ]
Kim, H. S. [1 ]
机构：
[1] Pochon CHA Univ, Coll Med, Dept Neurol, Songnam, Gyeunggido, South Korea
[2] Pochon CHA Univ, Coll Med, Dept Radiol, Songnam, Gyeunggido, South Korea
来源：
EUROPEAN JOURNAL OF NEUROLOGY | 2008年 / 15卷 / 03期
关键词：
cardioembolism; cerebral infarction; sildenafil;
D O I：
10.1111/j.1468-1331.2007.02025.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Sildenafil citrate (Viagra((R))) is one of the frequently prescribed drugs for men with erectile dysfunction. We describe a 52-year-old man with bilateral middle cerebral artery (MCA) territory infarction after sildenafil use. He ingested 100 mg of sildenafil and about 1 h later, he complained of chest discomfort, palpitation and dizziness followed by mental obtundation, global aphasia and left hemiparesis. Brain magnetic resonance imaging documented acute bilateral hemispheric infarction, and cerebral angiography showed occluded bilateral MCA. Despite significant bilateral MCA stenosis and cerebral infarction, systemic hypotension persisted for a day. We presume that cerebral infarction was caused by cardioembolism with sildenafil use.
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收藏
页码：306 / 308
页数：3
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