Serum pneumoproteins in firefighters

被引：6

作者：

Greven, Frans ^{[1
,2
]}

Krop, Esmeralda ^{[2
]}

Burger, Nena ^{[2
]}

Kerstjens, Huib ^{[3
]}

Heederik, Dick ^{[2
,4
]}

机构：

[1] Hulpverleningsdienst Groningen, Municipal Hlth Serv, Dept Environm Hlth, NL-9700 AN Groningen, Netherlands

[2] Univ Utrecht, Inst Risk Assessment Sci, Div Environm Epidemiol, Utrecht, Netherlands

[3] Univ Groningen, Univ Med Ctr Groningen, Dept Pulm Dis, Groningen, Netherlands

[4] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands

来源：

BIOMARKERS | 2011年 / 16卷 / 04期

关键词：

Bronchial hyperresponsiveness; Clara cell protein; surfactant-associated protein A; CLARA CELL PROTEIN; GARBAGE COLLECTORS; HEALTH-HAZARDS; SP-A; EXPOSURE; ASTHMA; CC16; BIOMARKER; INJURY; DETERMINANTS;

D O I：

10.3109/1354750X.2011.578218

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Serum Clara cell protein (CC16) and surfactant-associated protein A (SP-A) were measured in a cross-sectional study in 402 firefighters. For the population as a whole, no associations were detected between serum pneumoproteins and smoke exposure. SP-A levels were increased in symptomatic subjects exposed to fire smoke within 2 days before testing. SP-A levels were higher after an inhalation incident ever. CC16 was negatively associated with the number of fires fought in the last 12 months in current nonsmokers. These associations between pneumoprotein levels reiterate the importance of adequate use of self-contained breathing apparatus by firefighters.

引用

页码：364 / 371

页数：8

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