Rapid multispectral endoscopic imaging system for near real-time mapping of the mucosa blood supply in the lung

被引：22

作者：

Fawzy, Yasser ^{[1
]}

Lam, Stephen ^{[1
,2
]}

Zeng, Haishan ^{[1
,3
]}

机构：

[1] British Columbia Canc Agcy, Res Ctr, Imaging Unit, Integrat Oncol Dept, Vancouver, BC V5Z 1L3, Canada

[2] Univ British Columbia, Dept Med, Div Resp Med, Vancouver, BC V5Z 1M9, Canada

[3] Univ British Columbia, Dept Dermatol & Skin Sci, Photomed Inst, Vancouver, BC V5Z 4E8, Canada

来源：

BIOMEDICAL OPTICS EXPRESS | 2015年 / 6卷 / 08期

基金：

加拿大健康研究院;

关键词：

RADIATIVE TRANSPORT; IN-VIVO; REFLECTANCE SPECTROSCOPY; DELTA-P-1; APPROXIMATION; CANCER; TISSUE; MEDIA;

D O I：

10.1364/BOE.6.002980

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have developed a fast multispectral endoscopic imaging system that is capable of acquiring images in 18 optimized spectral bands spanning 400-760 nm by combining a customized light source with six triple-band filters and a standard color CCD camera. A method is developed to calibrate the spectral response of the CCD camera. Imaging speed of 15 spectral image cubes/second is achieved. A spectral analysis algorithm based on a linear matrix inversion approach is developed and implemented in a graphics processing unit (GPU) to map the mucosa blood supply in the lung in vivo. Clinical measurements on human lung patients are demonstrated. (C)2015 Optical Society of America

引用

收藏

页码：2980 / 2990

页数：11

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