The asymmetric oxidation of sulfides catalyzed by chiral oxazoline-Ti(IV) complexes

被引：0

作者：

Peng, YG

Feng, XM ^{[1
]}

Cui, X

Jiang, YZ

机构：

[1] Sichuan Univ, Fac Chem, Chengdu 610064, Peoples R China

[2] Chinese Acad Sci, Chengdu Inst Organ Chem, Union Lab Asymmetr Synth, Chengdu 610041, Peoples R China

来源：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2001年 / 22卷 / 08期

关键词：

oxazoline-Ti(O ' Pr)(4) complex; catalysis; sulfide; asymmetric oxidation;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of new chiral oxazoline-Ti (O Tr-i)(4) complexes were synthesized, which were firstly and successfully applied to the catalytic asymmetric oxidation of sulfides and resulted in chiral sulfoxides. The reactivity and enantioselectivity were strongly influenced by the structure of the oxazolines. When (4S, 5S)-4,5-dihydro-4,5-diphenyl-2-(2 ' -hydroxy-3 ' -tert-butylphenyl) oxazoline was used as the figand, 2. 0 mol of TBHP was used in the oxidation of methyl phenyl sulfide, the sulfoxide was obtained in 96% e. e.. The influence of solvent, amount of catalyst, counterion and other conditions on the reaction was also investigated.

引用

页码：1326 / 1331

页数：6

共 30 条

[1] Titanium-catalyzed, asymmetric sulfoxidation of alkyl aryl sulfides with optically active hydroperoxides [J].