Lolium perenne peptides for treatment of grass pollen allergy: A randomized, double-blind, placebo-controlled clinical trial

被引:19
作者
Shamji, Mohamed H. [1 ]
Ceuppens, Jan [3 ]
Bachert, Claus [2 ]
Hellings, Peter [4 ]
Placier, Gael [5 ]
Thirion, Gaetan [5 ]
Bovy, Nicolas [5 ]
Durham, Stephen R. [1 ]
Duchateau, Jean [5 ]
Legon, Thierry [5 ]
Pirotton, Sabine [5 ]
机构
[1] Imperial Coll London, MRC Asthma UK Ctr, Immunomodulat & Tolerance Grp, Allergy & Clin Immunol Inflammat Repair & Dev, London, England
[2] Univ Ghent, Upper Airways Res Lab, Ghent, Belgium
[3] UZ Leuven, Dept Allergy & Clin Immunol, Leuven, Belgium
[4] UZ Leuven, Ear Nose & Throat Dept, Leuven, Belgium
[5] ASIT Biotech, Brussels, Belgium
关键词
IMMUNOTHERAPY; SET;
D O I
10.1016/j.jaci.2017.09.013
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:448 / +
页数:8
相关论文
共 11 条
[1]   A set of pBR322-compatible plasmids allowing the testing of chaperone-assisted folding of proteins overexpressed in Escherichia coli [J].
Castanie, HP ;
Berges, H ;
Oreglia, J ;
Prere, MF ;
Fayet, O .
ANALYTICAL BIOCHEMISTRY, 1997, 254 (01) :150-152
[2]   Type I interferonopathies: a novel set of inborn errors of immunity [J].
Crow, Yanick J. .
YEAR IN HUMAN AND MEDICAL GENETICS: INBORN ERRORS OF IMMUNITY I, 2011, 1238 :91-98
[3]  
Fujimura Takashi, 2010, Allergology International, V59, P21, DOI 10.2332/allergolint.09-RAI-0151
[4]   COMPLEMENTARY-DNA CLONING OF THE MAJOR ALLERGEN PHL-P-I FROM TIMOTHY GRASS (PHLEUM-PRATENSE) - RECOMBINANT PHL-P-I INHIBITS IGE BINDING TO GROUP-I ALLERGENS FROM 8 DIFFERENT GRASS SPECIES [J].
LAFFER, S ;
VALENTA, R ;
VRTALA, S ;
SUSANI, M ;
VANREE, R ;
KRAFT, D ;
SCHEINER, O ;
DUCHENE, M .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1994, 94 (04) :689-698
[5]  
Noon L, 1911, LANCET, V1, P1572
[6]   Fel d 1-derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: A randomized, placebo-controlled study [J].
Patel, Deepen ;
Couroux, Peter ;
Hickey, Pascal ;
Salapatek, Anne Marie ;
Laidler, Paul ;
Larche, Mark ;
Hafner, Roderick P. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 131 (01) :103-U158
[7]   Ara h 1 CD4+T cell epitope-based peptides: candidates for a peanut allergy therapeutic [J].
Prickett, S. R. ;
Voskamp, A. L. ;
Phan, T. ;
Dacumos-Hill, A. ;
Mannering, S. I. ;
Rolland, J. M. ;
O'Hehir, R. E. .
CLINICAL AND EXPERIMENTAL ALLERGY, 2013, 43 (06) :684-697
[8]   Safety and immunogenicity of immunotherapy with Bet v 1-derived contiguous overlapping peptides [J].
Spertini, Francois ;
Perrin, Yannick ;
Audran, Regine ;
Pellaton, Celine ;
Boudousquie, Caroline ;
Barbier, Nathalie ;
Thierry, Anne-Christine ;
Charlon, Vincent ;
Reymond, Christophe .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (01) :239-U801
[9]   Relationship Between the Type I Interferon Signature and the Response to Rituximab in Rheumatoid Arthritis Patients [J].
Thurlings, Rogier M. ;
Boumans, Marie ;
Tekstra, Janneke ;
van Roon, Joel A. ;
Vos, Koen ;
van Westing, Daisy Marie ;
van Baarsen, Lisa G. ;
Bos, Carina ;
Kirou, Kyriakos A. ;
Gerlag, Danielle M. ;
Crow, Mary K. ;
Bijlsma, Johannes W. ;
Verweij, Cornelis L. ;
Tak, Paul P. .
ARTHRITIS AND RHEUMATISM, 2010, 62 (12) :3607-3614
[10]   The role of protein digestibility and antacids on food allergy outcomes [J].
Untersmayr, Eva ;
Jensen-Jarolim, Erika .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2008, 121 (06) :1301-1308