A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

被引:232
作者
Klionsky, Daniel J. [1 ,2 ,3 ]
Baehrecke, Eric H. [4 ]
Brumell, John H. [5 ]
Chu, Charleen T. [6 ]
Codogno, Patrice [7 ,8 ]
Cuervo, Ana Maria [9 ]
Debnath, Jayanta [10 ]
Deretic, Vojo [11 ]
Elazar, Zvulun [12 ]
Eskelinen, Eeva-Liisa [13 ]
Finkbeiner, Steven [14 ,15 ,16 ]
Fueyo-Margareto, Juan [17 ]
Gewirtz, David [18 ]
Jaattela, Marja [19 ]
Kroemer, Guido [20 ]
Levine, Beth [21 ,22 ]
Melia, Thomas J. [23 ]
Mizushima, Noboru [24 ]
Rubinsztein, David C. [25 ]
Simonsen, Anne [26 ]
Thorburn, Andrew [27 ]
Thumm, Michael [28 ]
Tooze, Sharon A. [29 ]
机构
[1] Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biol Chem, Ann Arbor, MI 48109 USA
[4] Univ Massachusetts, Sch Med, Dept Canc Biol, Worcester, MA USA
[5] Hosp Sick Children, Cell Biol Program, Toronto, ON M5G 1X8, Canada
[6] Univ Pittsburgh, Sch Med, Dept Pathol, Pittsburgh, PA USA
[7] INSERM, U984, Chatenay Malabry, France
[8] Univ Paris 11, Chatenay Malabry, France
[9] Albert Einstein Coll Med, Inst Aging Res, Marion Bessin Liver Res Ctr, Dept Dev & Mol Biol, Bronx, NY 10467 USA
[10] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94140 USA
[11] Univ New Mexico, Hlth Sci Ctr, Dept Mol Genet & Microbiol, Albuquerque, NM 87131 USA
[12] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel
[13] Univ Helsinki, Dept Biosci, Helsinki, Finland
[14] Univ Calif San Francisco, Gladstone Inst Neurol Dis, San Francisco, CA 94143 USA
[15] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
[16] Univ Calif San Francisco, Dept Physiol, San Francisco, CA USA
[17] Univ Texas Houston, MD Anderson Canc Ctr, Dept Neurooncol, Houston, TX 77030 USA
[18] Virginia Commonwealth Univ, Massey Canc Ctr, Richmond, VA USA
[19] Danish Canc Soc, Dept Apoptosis, Copenhagen, Denmark
[20] Univ Paris 05, Fac Med, INSERM, Ctr Rech Cordeliers,U872, Paris, France
[21] Univ Texas SW Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX 75390 USA
[22] Univ Texas SW Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA
[23] Yale Univ, Dept Cell Biol, New Haven, CT USA
[24] Tokyo Med & Dent Univ, Dept Physiol & Cell Biol, Tokyo, Japan
[25] Cambridge Inst Med Res, Dept Med Genet, Cambridge, England
[26] Univ Oslo, Dept Biochem, Inst Basic Med Sci, Oslo 3, Norway
[27] Univ Colorado, Ctr Canc, Dept Pharmacol, Denver, CO 80262 USA
[28] Univ Gottingen, Zentrum Biochem & Mol Zellbiol, Gottingen, Germany
[29] Canc Res UK, London Res Inst, London, England
关键词
autophagy; lysosome; mitophagy; pexophagy; stress; vacuole; ACTIVATED PROTEIN-KINASE; STARVATION-INDUCED AUTOPHAGY; VACUOLE TARGETING PATHWAY; COILED-COIL PROTEIN; REGULATES AUTOPHAGY; CELL-DEATH; AMINOPEPTIDASE-I; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL; 3-PHOSPHATE; PIECEMEAL MICROAUTOPHAGY;
D O I
10.4161/auto.7.11.17661
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The study of autophagy is rapidly expanding, and our knowledge of the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. The vocabulary associated with autophagy has grown concomitantly. In fact, it is difficult for readers-even those who work in the field-to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors and chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, and the roles of accessory components and structures that are associated with autophagy.
引用
收藏
页码:1273 / 1294
页数:22
相关论文
共 329 条
  • [1] Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p
    Abeliovich, H
    Darsow, T
    Emr, SD
    [J]. EMBO JOURNAL, 1999, 18 (21) : 6005 - 6016
  • [2] ABRAHAMSEN H, 2010, J BIOL CHEM, V20, P415
  • [3] An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation
    Agarraberes, FA
    Terlecky, SR
    Dice, JF
    [J]. JOURNAL OF CELL BIOLOGY, 1997, 137 (04) : 825 - 834
  • [4] Laforin, the most common protein mutated in Lafora disease, regulates autophagy
    Aguado, Carmen
    Sarkar, Sovan
    Korolchuk, Viktor I.
    Criado, Olga
    Vernia, Santiago
    Boya, Patricia
    Sanz, Pascual
    Rodriguez de Cordoba, Santiago
    Knecht, Erwin
    Rubinsztein, David C.
    [J]. HUMAN MOLECULAR GENETICS, 2010, 19 (14) : 2867 - 2876
  • [5] LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
    Alegre-Abarrategui, Javier
    Christian, Helen
    Lufino, Michele M. P.
    Mutihac, Ruxandra
    Venda, Lara Lourenco
    Ansorge, Olaf
    Wade-Martins, Richard
    [J]. HUMAN MOLECULAR GENETICS, 2009, 18 (21) : 4022 - 4034
  • [6] ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
    Alexander, Angela
    Cai, Sheng-Li
    Kim, Jinhee
    Nanez, Adrian
    Sahin, Mustafa
    MacLean, Kirsteen H.
    Inoki, Ken
    Guan, Kun-Liang
    Shen, Jianjun
    Person, Maria D.
    Kusewitt, Donna
    Mills, Gordon B.
    Kastan, Michael B.
    Walker, Cheryl Lyn
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (09) : 4153 - 4158
  • [7] Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
    Arndt, Verena
    Dick, Nikolaus
    Tawo, Riga
    Dreiseidler, Michael
    Wenzel, Daniela
    Hesse, Michael
    Fuerst, Dieter O.
    Saftig, Paul
    Saint, Robert
    Fleischmann, Bernd K.
    Hoch, Michael
    Hoehfeld, Joerg
    [J]. CURRENT BIOLOGY, 2010, 20 (02) : 143 - 148
  • [8] FoxO3 controls dangerous proteolytic liaisons
    Attaix, Didier
    Bechet, Daniel
    [J]. CELL METABOLISM, 2007, 6 (06) : 425 - 427
  • [9] Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
    Axe, Elizabeth L.
    Walker, Simon A.
    Manifava, Maria
    Chandra, Priya
    Roderick, H. Llewelyn
    Habermann, Anja
    Griffiths, Gareth
    Ktistakis, Nicholas T.
    [J]. JOURNAL OF CELL BIOLOGY, 2008, 182 (04) : 685 - 701
  • [10] Analysis of the membrane structures involved in autophagy in yeast by freeze-replica method
    Baba, M
    Osumi, M
    Ohsumi, Y
    [J]. CELL STRUCTURE AND FUNCTION, 1995, 20 (06) : 465 - 471