Tributyltin hydride and 1-ethylpiperidine hypophosphite mediated intermolecular radical additions to 2,4,6-trichlorophenyl vinyl sulfonate

被引：7

作者：

Edetanlen-Elliot, Oluwabusola ^{[1
]}

Fitzmaurice, Richard J. ^{[1
]}

Wilden, Jonathan D. ^{[1
]}

Caddick, Stephen ^{[1
]}

机构：

[1] UCL, Christopher Ingold Labs, Dept Chem, London WC1H 0AJ, England

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 50期

基金：

英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

radical addition; tributyltin hydride; EPHP; TCP-sulfonate; sulfonamide;

D O I：

10.1016/j.tetlet.2007.10.030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,4,6-Trichlorophenyl vinyl sulfonate smoothly undergoes intermolecular radical addition under mild initiation conditions mediated by tributyltin hydride and 1-ethylpiperidine hypophosphite (EPHP) to generate a range of functionalised alkyl sulfonamide precursors. This methodology can be used to prepare bifunctional pentafluorophenyl/2,4,6-trichlorophenyl sulfonates in good yields. (c) 2007 Published by Elsevier Ltd.

引用

页码：8926 / 8929

页数：4

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